1-Ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Base Information

Chemical Name:1-Ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS No.:23789-88-0
Molecular Formula:C12H11 N O3
Molecular Weight:217.224
Hs Code.:2933499090
DSSTox Substance ID:DTXSID30364167
Nikkaji Number:J468.268H
Wikidata:Q82147965
ChEMBL ID:CHEMBL4461140
Mol file:23789-88-0.mol

Synonyms:1-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;23789-88-0;1-ethyl-4-oxoquinoline-3-carboxylic acid;SCHEMBL1661468;CHEMBL4461140;DTXSID30364167;BBL003097;MFCD00667561;STK411484;AKOS000280861;BS-3257;SB68875;FT-0684368;A878141;1-ethyl-1,4-dihydro-4-oxo-quinoline-3-carboxylic;1,4-Dihydro-1-ethyl-4-oxoquinoline-3-carboxylic acid;1-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylicacid

Suppliers and Price of 1-Ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylicAcid
500mg
$ 265.00

Matrix Scientific
1-Ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
500mg
$ 237.00

Crysdot
1-Ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 95+%
10g
$ 942.00

Crysdot
1-Ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 95+%
5g
$ 658.00

Chemenu
1-Ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 95%
5g
$ 622.00

Chemenu
1-Ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 95%
10g
$ 888.00

ChemBridge Corporation
1-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 95%
1 g
$ 185.00

Alichem
1-Ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylicacid
10g
$ 969.00

Alichem
1-Ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylicacid
5g
$ 691.60

AK Scientific
1-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylicacid
1g
$ 400.00

Total 8 raw suppliers

Chemical Property of 1-Ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Chemical Property:

Melting Point:253-254 °C (decomp)(Solv: N,N-dimethylformamide (68-12-2))
Boiling Point:357.8±42.0 °C(Predicted)
PKA:0.78±0.20(Predicted)
PSA：59.30000
Density:1.317±0.06 g/cm3(Predicted)
LogP:1.71960
Storage Temp.:2-8°C
XLogP3:0
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:217.07389321
Heavy Atom Count:16
Complexity:348

Purity/Quality:

97% ^*data from raw suppliers

1-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1C=C(C(=O)C2=CC=CC=C21)C(=O)O

Technology Process of 1-Ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

There total 2 articles about 1-Ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 52980-28-6
ethyl 4-oxo-1,4-dihydroquinoline-3-carboxylate

: 23789-88-0
1-ethyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 18 h / 40 - 80 °C

2: sodium hydroxide; water / 2 h / 100 °C

With water; potassium carbonate; sodium hydroxide; In N,N-dimethyl-formamide;

Reference yield:

: 52980-28-6
ethyl 4-oxo-1,4-dihydroquinoline-3-carboxylate

: 75-03-6
ethyl iodide

: 23789-88-0
1-ethyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

Guidance literature:: With potassium tert-butylate; Yield given. Multistep reaction; 1.) DMF, RT, 1.5 h, 2.) DMF, RT, 6 h;
DOI:10.1248/cpb.40.692