3H-2-Benzopyran-3-one, 1,4-dihydro-8-hydroxy-7-(phenylmethoxy)-

Base Information

Chemical Name:3H-2-Benzopyran-3-one, 1,4-dihydro-8-hydroxy-7-(phenylmethoxy)-
CAS No.:65615-22-7
Molecular Formula:C16H14O4
Molecular Weight:270.285
Hs Code.:

Synonyms:

Suppliers and Price of 3H-2-Benzopyran-3-one, 1,4-dihydro-8-hydroxy-7-(phenylmethoxy)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 6 raw suppliers

Chemical Property of 3H-2-Benzopyran-3-one, 1,4-dihydro-8-hydroxy-7-(phenylmethoxy)-

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3H-2-Benzopyran-3-one, 1,4-dihydro-8-hydroxy-7-(phenylmethoxy)-

There total 5 articles about 3H-2-Benzopyran-3-one, 1,4-dihydro-8-hydroxy-7-(phenylmethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 28988-68-3
2-(4-(benzyloxy)-3-hydroxyphenyl)acetic acid

: 65615-22-7
7-(benzyloxy)-8-hydroxy-1H-isochromen-3(4H)-one

Guidance literature:: 2-(4-(benzyloxy)-3-hydroxyphenyl)acetic acid; With phenylboronic acid; In toluene; for 1h; Reflux; Dean-Stark;

formaldehyd; In toluene; at 100 ℃; for 46h; Molecular sieve; Sealed tube;

In water; for 2h; Reflux;
DOI:10.1016/j.bmc.2012.12.016

Reference yield:

: 14199-15-6
Methyl 4-hydroxyphenylacetate

: 65615-22-7
7-(benzyloxy)-8-hydroxy-1H-isochromen-3(4H)-one

Guidance literature:: Multi-step reaction with 4 steps

1.1: acetic acid; bromine / 2 h / 20 °C

2.1: potassium carbonate / acetone / Reflux

3.1: potassium hydroxide; water; copper; copper(II) oxide / 1 h / 140 °C / Inert atmosphere; Microwave irradiation

4.1: phenylboronic acid / toluene / 1 h / Reflux; Dean-Stark

4.2: 46 h / 100 °C / Molecular sieve; Sealed tube

4.3: 2 h / Reflux

With water; bromine; copper; potassium carbonate; acetic acid; copper(II) oxide; potassium hydroxide; phenylboronic acid; In acetone; toluene;
DOI:10.1016/j.bmc.2012.12.016

Reference yield:

: 34918-57-5
methyl 3-bromo-4-hydroxyphenylacetate

: 65615-22-7
7-(benzyloxy)-8-hydroxy-1H-isochromen-3(4H)-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium carbonate / acetone / Reflux

2.1: potassium hydroxide; water; copper; copper(II) oxide / 1 h / 140 °C / Inert atmosphere; Microwave irradiation

3.1: phenylboronic acid / toluene / 1 h / Reflux; Dean-Stark

3.2: 46 h / 100 °C / Molecular sieve; Sealed tube

3.3: 2 h / Reflux

With water; copper; potassium carbonate; copper(II) oxide; potassium hydroxide; phenylboronic acid; In acetone; toluene;
DOI:10.1016/j.bmc.2012.12.016