L-Valine, N-benzoyl-3-methyl-, methyl ester

Base Information

Chemical Name:L-Valine, N-benzoyl-3-methyl-, methyl ester
CAS No.:65718-51-6
Molecular Formula:C14H19NO3
Molecular Weight:249.30600
Hs Code.:
Mol file:65718-51-6.mol

Synonyms:(S)-2-Benzoylamino-3,3-dimethyl-butyric acid methyl ester;N-benzoyl-L-tert-leucine methyl ester;

Suppliers and Price of L-Valine, N-benzoyl-3-methyl-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of L-Valine, N-benzoyl-3-methyl-, methyl ester

Chemical Property:

PSA：55.40000
LogP:2.39500

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of L-Valine, N-benzoyl-3-methyl-, methyl ester

There total 8 articles about L-Valine, N-benzoyl-3-methyl-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 63038-26-6
(S)-2-amino-3,3-dimethyl-butyric acid methyl ester

: 93-97-0
benzoic acid anhydride

: 65718-51-6,147701-18-6
(2S)-methyl 2-benzoylamino-3,3-dimethylbutanoate

Guidance literature:: benzoic acid anhydride; With molybdenium(VI) dioxodichloride; In dichloromethane; at 20 ℃; for 0.5h;

(S)-2-amino-3,3-dimethyl-butyric acid methyl ester; In dichloromethane; at 20 ℃; for 12h;
DOI:10.1021/jo048363v

Reference yield:

: 67-56-1
methanol

: 71953-55-4
2-phenyl-4-tert-butyloxazolin-5(4H)-one

: 65718-51-6,147701-18-6
(2S)-methyl 2-benzoylamino-3,3-dimethylbutanoate

: 147701-18-6
(R)-2-Benzoylamino-3,3-dimethyl-butyric acid methyl ester

Guidance literature:: With Lipozyme-Mucor miehei; triethylamine; In toluene; at 30 ℃; for 264h; Yield given. Yields of byproduct given;
DOI:10.1016/0040-4039(94)02408-4

Reference yield:

: 33105-81-6
2-amino-3,3-dimethylbutanoic acid

: 65718-51-6,147701-18-6
(2S)-methyl 2-benzoylamino-3,3-dimethylbutanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaOH; 2.) Ac₂O

2: Lipozyme-Mucor miehei, triethylamine / toluene / 264 h / 30 °C

With sodium hydroxide; Lipozyme-Mucor miehei; acetic anhydride; triethylamine; In toluene;
DOI:10.1016/0040-4039(94)02408-4