Methyl 3-(2-furyl)propanoate

Base Information

• Chemical Name: Methyl 3-(2-furyl)propanoate
• CAS No.: 37493-31-5
• Molecular Formula: C8H10O3
• Molecular Weight: 154.1632
• NSC Number: 97519
• DSSTox Substance ID: DTXSID50294639
• Nikkaji Number: J464.789K
• Wikidata: Q82034028
• Mol file: 37493-31-5.mol

Synonyms:methyl 3-(2-furyl)propanoate;37493-31-5;methyl 3-(furan-2-yl)propanoate;NSC97519;methyl 3-(2-furyl)propionate;2-(2'-carbomethoxyethyl)furan;SCHEMBL5883913;methyl 3-(furan-2-yl)propanate;DTXSID50294639;Methyl 3-(furan-2-yl)propionate;UXHQPGLQTVKTBI-UHFFFAOYSA-N;NSC-97519;AKOS008909720

Chemical Property of Methyl 3-(2-furyl)propanoate

Chemical Property:

• Vapor Pressure: 0.429mmHg at 25°C
• Boiling Point: 195°Cat760mmHg
• Flash Point: 83.1°C
• Density: 1.089g/cm³
• XLogP3: 1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 154.062994177
• Heavy Atom Count: 11
• Complexity: 133

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)CCC1=CC=CO1

Technology Process of Methyl 3-(2-furyl)propanoate

There total 13 articles about Methyl 3-(2-furyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

methyl 3-(2-furyl)acrylate (58293-85-9) → methyl 3-(2-furyl)propionate (37493-31-5)

Guidance literature:

With hydrogen; Wilkinson's catalyst; In tetrahydrofuran; at 45 ℃; under 2585.74 Torr;

DOI:10.1016/j.bmcl.2005.06.090

Reference yield: 92.0%

methanol (67-56-1) + 3-(2-furyl)propionaldehyde (4543-51-5) → methyl 3-(2-furyl)propionate (37493-31-5)

Guidance literature:

With manganese(IV) oxide; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,4-dimethyl-1,2,4-triazolium iodide; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1021/ol8018488

Reference yield: 91.0%

methanol (67-56-1) + 3-(2-furyl)propanoic acid (935-13-7) → methyl 3-(2-furyl)propionate (37493-31-5)

Guidance literature:

With sulfuric acid; Heating;

upstream raw materials:

diazomethane

3-(2-furyl)propanoic acid

methyl 3-(2-furyl)acrylate

methanol

Downstream raw materials:

N-phenyl-3-(furan-2-yl)propanamide

3-furan-2-yl-propan-1-ol

4-(furan-2-yl)-3-(toluene-4-sulfonyloxmethyl)butyric acid tert-butyl ester

N₁,N₂-bis(benzyloxycarbonyl)-N₁-(3-{5-[(dimethylamino)methyl]furan-2-yl}propyl)guanidine