Acetamide, N-(3-amino-4-nitrophenyl)-

Base Information

• Chemical Name: Acetamide, N-(3-amino-4-nitrophenyl)-
• CAS No.: 66136-64-9
• Molecular Formula: C8H9N3O3
• Molecular Weight: 195.178
• DSSTox Substance ID: DTXSID30394161
• Wikidata: Q82193397
• Mol file: 66136-64-9.mol

Synonyms:Acetamide, N-(3-amino-4-nitrophenyl)-;66136-64-9;N-(3-amino-4-nitrophenyl)acetamide;N-{3-amino-4-nitrophenyl}acetamide;SCHEMBL4271625;DTXSID30394161;AE-562/12222410

Chemical Property of Acetamide, N-(3-amino-4-nitrophenyl)-

Chemical Property:

• XLogP3: 0.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 195.06439116
• Heavy Atom Count: 14
• Complexity: 239

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])N

Technology Process of Acetamide, N-(3-amino-4-nitrophenyl)-

There total 3 articles about Acetamide, N-(3-amino-4-nitrophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

2,4-diaminonitrobenzene (5131-58-8) + acetyl chloride (75-36-5) → acetic acid-(3-amino-4-nitro-anilide) (66136-64-9)

Guidance literature:

2,4-diaminonitrobenzene; acetyl chloride; With pyridine; In tetrahydrofuran; acetonitrile;

With water; In tetrahydrofuran; acetonitrile; Product distribution / selectivity;

Reference yield:

2,4-diaminonitrobenzene (5131-58-8) + acetic acid (64-19-7,77671-22-8) → acetic acid-(3-amino-4-nitro-anilide) (66136-64-9) + N,N'-(4-nitro-m-phenylene)-bis-acetamide (119-76-6)

Guidance literature:

anschliessend mit Acetanhydrid;

DOI:10.1039/jr9300001910

Reference yield:

2,4-diaminonitrobenzene (5131-58-8) + acetic anhydride (108-24-7) → acetic acid-(3-amino-4-nitro-anilide) (66136-64-9)

Guidance literature:

With acetic acid;

upstream raw materials:

2,4-diaminonitrobenzene

acetic anhydride

acetic acid

acetyl chloride

Downstream raw materials:

(5-acetylamino-2-nitro-phenyl)-arsonic acid

(2,5-diamino-phenyl)-arsonic acid

2-hydroxy-4-amino-1-nitrobenzene

3-hydroxy-4-nitroacetanilide