119-76-6 Usage
Uses
Used in Pharmaceutical Synthesis:
N,N'-(4-nitro-1,3-phenylene)bis(acetamide) is utilized as an intermediate in the production of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Organic Compounds Synthesis:
N,N'-(4-nitro-1,3-phenylene)bis(acetamide) also serves as an intermediate in the synthesis of organic compounds, playing a crucial role in the creation of complex organic molecules for various applications.
Used in Research and Development:
In the realm of research and development, N,N'-(4-nitro-1,3-phenylene)bis(acetamide) is explored for its potential applications in anti-cancer and anti-inflammatory drugs, indicating its importance in the advancement of medical treatments.
Used in Anti-Cancer Drug Development:
N,N'-(4-nitro-1,3-phenylene)bis(acetamide) is used as a precursor in the development of anti-cancer drugs, where it may contribute to the creation of novel therapeutic agents targeting cancer cells.
Used in Anti-Inflammatory Drug Development:
Similarly, N,N'-(4-nitro-1,3-phenylene)bis(acetamide) is employed in the research and development of anti-inflammatory drugs, potentially aiding in the discovery of new treatments for inflammatory conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 119-76-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,1 and 9 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 119-76:
(5*1)+(4*1)+(3*9)+(2*7)+(1*6)=56
56 % 10 = 6
So 119-76-6 is a valid CAS Registry Number.
119-76-6Relevant academic research and scientific papers
Synthesis and characterization of selected 4,4′-diaminoalkoxyazobenzenes
Jeong, Euigyung,Freeman, Harold S.,Claxton, Larry D.
experimental part, p. 100 - 108 (2010/12/18)
The role of the -N(CH2CH2OH)2 group in producing a mutagenic response from 4-((3-(2-hydroxyethoxy)4-amino)phenylazo)-N,N-bis(2-hydroxyethyl)aniline has been investigated. To accomplish this goal, a group of substituted 4,4′-diaminoazobenzene dyes was synthesized, and their structures were confirmed using 1H NMR, TOF-LC-ESI mass spectrometry, and combustion analysis. Mutagenicity was determined using the standard Ames test in Salmonella strains TA98, TA100, and TA1538 with and without S9 enzyme activation. The results of this study provide evidence that the mutagenicity of the parent dye arises from the metabolic cleavage of N-hydroxyethyl groups to give the corresponding -NHCH2CH2OH and -NH2 substituted monoazo dyes as direct-acting mutagens. All 5 of the dyes studied were mutagenic at various levels with and without S9 enzyme activation in TA1538. In addition, the results show that removing one N-hydroxyethyl group and capping both -OH groups in the parent dye did not affect mutagenicity, whereas removing both N-hydroxyethyl groups produced a strong direct-acting mutagen in all three bacterial strains. Increasing the length of the N-alkyl chain from two to three carbon atoms eliminated mutagenicity in TA98 without S9 activation.
