2-iodo-4-nitrophenyl phenyl ether

Base Information

• Chemical Name: 2-iodo-4-nitrophenyl phenyl ether
• CAS No.: 66166-42-5
• Molecular Formula: C12H8INO3
• Molecular Weight: 341.10100
• Mol file: 66166-42-5.mol

Synonyms:2-Iodo-4-nitro-1-phenoxy-benzene;1-(2-iodo-4-nitrophenoxy)benzene;(2-iodo-4-nitro-phenyl)-phenyl ether;3-iodo-4-phenoxy-nitro-benzene;2-Jod-4-nitro-diphenylaether;2-iodo-4-nitrophenyl ether;(2-Jod-4-nitro-phenyl)-phenyl-aether;

Chemical Property of 2-iodo-4-nitrophenyl phenyl ether

Chemical Property:

• PSA: 55.05000
• LogP: 4.51490

Purity/Quality:

2-iodo-4-nitro-1-phenoxybenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-iodo-4-nitrophenyl phenyl ether

There total 14 articles about 2-iodo-4-nitrophenyl phenyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + [bis(acetoxy)iodo]benzene (3240-34-4) → 2-iodo-4-nitro-1-phenoxybenzene (66166-42-5)

Guidance literature:

With Trimethylacetic acid; In 1,2-dichloro-ethane; at 80 ℃; for 12h;

DOI:10.1021/acs.joc.5b00634

Reference yield: 58.0%

2-hydroxy-5-nitrodiphenyliodonium ylide (72212-81-8) → 2-iodo-4-nitro-1-phenoxybenzene (66166-42-5) + 2-iodo-4-nitrophenol (89487-91-2)

Guidance literature:

With sodium methylate; In methanol; Inert atmosphere; Reflux;

DOI:10.1007/s11164-015-2373-y

Reference yield: 47.0%

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + [bis(acetoxy)iodo]benzene (3240-34-4) → 2-iodo-4-nitro-1-phenoxybenzene (66166-42-5) + 1,3-diiodo-5-nitro-2-phenoxybenzene

Guidance literature:

4-nitro-phenol; [bis(acetoxy)iodo]benzene; In methanol; for 0.333333h; Inert atmosphere;

With sodium methylate; In methanol; Inert atmosphere; Heating;

DOI:10.1007/s11164-015-2373-y

upstream raw materials:

4-nitro-phenol

[bis(acetoxy)iodo]benzene

5-nitro-2-phenoxy-aniline

(2-hydroxy-5-nitro-phenyl)-phenyl-iodonium ; acetate

Downstream raw materials:

3-iodo-4-phenoxy-aniline

(2,4-diiodo-phenyl)-phenyl ether

2-nitrodibenzofuran