Ethyl 2-(2-methoxy-2-oxoethyl)benzoate

Base Information

Chemical Name:Ethyl 2-(2-methoxy-2-oxoethyl)benzoate
CAS No.:66298-59-7
Molecular Formula:C12H14O4
Molecular Weight:222.241
Hs Code.:
DSSTox Substance ID:DTXSID20494881
Wikidata:Q82342596

Synonyms:66298-59-7;Ethyl 2-(2-methoxy-2-oxoethyl)benzoate;2-(Ethoxycarbonyl) Methyl Ester Benzeneacetic Acid;DTXSID20494881

Suppliers and Price of Ethyl 2-(2-methoxy-2-oxoethyl)benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Ethyl 2-(2-methoxy-2-oxoethyl)benzoate

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:222.08920892
Heavy Atom Count:16
Complexity:249

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC=CC=C1CC(=O)OC

Technology Process of Ethyl 2-(2-methoxy-2-oxoethyl)benzoate

There total 4 articles about Ethyl 2-(2-methoxy-2-oxoethyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.4%

: 14736-50-6
o-(methoxycarbonylmethyl)benzoic acid

: 75-03-6
ethyl iodide

: 66298-59-7
methyl 2-ethoxycarbonylphenylacetate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; for 1h; Ambient temperature;
DOI:10.1016/S0040-4020(01)86002-6

Reference yield:

: 89-51-0
Homophthalic acid

: 66298-59-7
methyl 2-ethoxycarbonylphenylacetate

Guidance literature:: Multi-step reaction with 2 steps

1: 82.4 percent / H₂SO₄ / 1.5 h / Heating

2: 82.4 percent / K₂CO₃ / dimethylformamide / 1 h / Ambient temperature

With sulfuric acid; potassium carbonate; In N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)86002-6