2-Bromotetrahydro-2H-pyran

Base Information

• Chemical Name: 2-Bromotetrahydro-2H-pyran
• CAS No.: 6667-26-1
• Molecular Formula: C5H9BrO
• Molecular Weight: 165.03
• European Community (EC) Number: 862-179-9
• Nikkaji Number: J1.713.646A
• Mol file: 6667-26-1.mol

Synonyms:2-bromooxane;2-Bromotetrahydro-2H-pyran;6667-26-1;bromotetrahydropyran;SCHEMBL2009272;EN300-269160

Chemical Property of 2-Bromotetrahydro-2H-pyran

Chemical Property:

• Boiling Point: 61 °C(Press: 16 Torr)
• PSA: 9.23000
• Density: 1.502 g/cm3(Temp: 8 °C)
• LogP: 1.90790
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 163.98368
• Heavy Atom Count: 7
• Complexity: 56

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CCOC(C1)Br

Technology Process of 2-Bromotetrahydro-2H-pyran

There total 1 articles about 2-Bromotetrahydro-2H-pyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-ethoxytetrahydropyran (4819-83-4) + 2-Bromoacetyl bromide (598-21-0) → 2-bromotetrahydropyran (6667-26-1) + ethyl bromoacetate (105-36-2)

Guidance literature:

at 0 ℃; for 5h;

DOI:10.1081/SCC-120002510

Reference yield: 43.0%

2-bromotetrahydropyran (6667-26-1) + vinylmagnesium chloride (3536-96-7) → 2-vinyltetrahydro-2H-pyran (52426-83-2)

Guidance literature:

In tetrahydrofuran; at -5 - 5 ℃;

DOI:10.1021/jm00017a016

upstream raw materials:

2-ethoxytetrahydropyran

2-Bromoacetyl bromide

Downstream raw materials:

2-vinyltetrahydro-2H-pyran