N-(N-((Phenylmethoxy)carbonyl)-L-phenylalanyl)-L-glutamic acid

Base Information

Chemical Name:N-(N-((Phenylmethoxy)carbonyl)-L-phenylalanyl)-L-glutamic acid
CAS No.:3617-46-7
Molecular Formula:C₂₂H₂₄N₂O₇
Molecular Weight:428.442
Hs Code.:
European Community (EC) Number:222-804-2
DSSTox Substance ID:DTXSID30189736
Nikkaji Number:J205.544I
Wikidata:Q83061938
Mol file:3617-46-7.mol

Synonyms:3617-46-7;N-(N-((Phenylmethoxy)carbonyl)-L-phenylalanyl)-L-glutamic acid;(2S)-2-[[(2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]pentanedioic acid;EINECS 222-804-2;SCHEMBL10397579;DTXSID30189736;MFCD00238495;N-[N-[(Phenylmethoxy)carbonyl]-L-phenylalanyl]-L-gultamic acid

Suppliers and Price of N-(N-((Phenylmethoxy)carbonyl)-L-phenylalanyl)-L-glutamic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Z-PHE-GLU-OH
50mg
$ 45.00

American Custom Chemicals Corporation
Z-PHE-GLU-OH 95.00%
5MG
$ 499.17

Total 7 raw suppliers

Chemical Property of N-(N-((Phenylmethoxy)carbonyl)-L-phenylalanyl)-L-glutamic acid

Chemical Property:

Vapor Pressure:1.58E-23mmHg at 25°C
Boiling Point:748.4°Cat760mmHg
Flash Point:406.4°C
PSA：149.01000
Density:1.325g/cm³
LogP:3.00300
XLogP3:2.2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:12
Exact Mass:428.15835111
Heavy Atom Count:31
Complexity:613

Purity/Quality:

99% ^*data from raw suppliers

Z-PHE-GLU-OH ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(C(=O)NC(CCC(=O)O)C(=O)O)NC(=O)OCC2=CC=CC=C2
Isomeric SMILES:C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)OCC2=CC=CC=C2

Technology Process of N-(N-((Phenylmethoxy)carbonyl)-L-phenylalanyl)-L-glutamic acid

There total 14 articles about N-(N-((Phenylmethoxy)carbonyl)-L-phenylalanyl)-L-glutamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6
L-glutamic acid

: 1161-13-3
N-Cbz-L-Phe

: 541-41-3
chloroformic acid ethyl ester

: 3617-46-7,17461-80-2,17461-81-3,17461-82-4
Cbz-L-Phe-L-Glu-OH

Guidance literature:: N-Cbz-L-Phe; chloroformic acid ethyl ester; With triethylamine; In tetrahydrofuran; at 0 ℃; for 0.5h;

L-glutamic acid; With sodium hydrogencarbonate; In tetrahydrofuran; water; at 0 ℃; for 0.5h;
DOI:10.1246/cl.2012.577

Reference yield: 88.0%

: 56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6
L-glutamic acid

: 2578-84-9
N-benzyloxycarbonyl-L-phenylalanine p-nitrophenyl ester

: 3617-46-7,17461-80-2,17461-81-3,17461-82-4
Cbz-L-Phe-L-Glu-OH

Guidance literature:: With sodium hydroxide; In water; butan-1-ol; Ambient temperature;

Reference yield: 83.0%

: 56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6
L-glutamic acid

: 2448-45-5
Cbz-D-Phe

: 541-41-3
chloroformic acid ethyl ester

: 3617-46-7,17461-80-2,17461-82-4,17461-81-3
Cbz-D-Phe-L-Glu-OH

Guidance literature:: Cbz-D-Phe; chloroformic acid ethyl ester; With triethylamine; In tetrahydrofuran; at 0 ℃; for 0.5h;

L-glutamic acid; In tetrahydrofuran; water; at 0 ℃; for 0.5h;
DOI:10.1246/cl.2012.577