5-(Trimethylsilyl)quinoline

Base Information

Chemical Name:5-(Trimethylsilyl)quinoline
CAS No.:67532-97-2
Molecular Formula:C12H15NSi
Molecular Weight:201.343
Hs Code.:
DSSTox Substance ID:DTXSID50497385
Wikidata:Q82346877

Synonyms:5-(Trimethylsilyl)quinoline;67532-97-2;trimethyl(quinolin-5-yl)silane;DTXSID50497385

Suppliers and Price of 5-(Trimethylsilyl)quinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 5-(Trimethylsilyl)quinoline

Chemical Property:

PSA：12.89000
LogP:2.78000
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:201.097376017
Heavy Atom Count:14
Complexity:197

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C[Si](C)(C)C1=CC=CC2=C1C=CC=N2

Technology Process of 5-(Trimethylsilyl)quinoline

There total 1 articles about 5-(Trimethylsilyl)quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4964-71-0
5-bromoquinoline

: 75-77-4
chloro-trimethyl-silane

: 67532-97-2
5-trimethylsilylquinoline

Guidance literature:: With n-butyllithium; Yield given. Multistep reaction; 1.) ether, hexane, -70 deg C, 10 min., 2.) room temp., overnight;
DOI:10.1016/0022-328X(91)83116-L

Reference yield:

: 100-59-4
phenylmagnesium chloride

: 67532-97-2
5-trimethylsilylquinoline

: C₁₈H₁₉NSi

Guidance literature:: phenylmagnesium chloride; 5-trimethylsilylquinoline; With N,N,N,N,-tetramethylethylenediamine; In toluene; at 50 ℃; for 10h; Glovebox; Inert atmosphere;

With oxygen; ammonium chloride; In water; toluene; at 0 ℃; for 12h;
DOI:10.1021/jacs.1c10743