ETHYL 2-BROMOACRYLATE

Base Information

• Chemical Name: ETHYL 2-BROMOACRYLATE
• CAS No.: 5459-35-8
• Molecular Formula: C5H7BrO2
• Molecular Weight: 179.013
• Hs Code.: 2916190090
• Mol file: 5459-35-8.mol

Synonyms:Acrylicacid, 2-bromo-, ethyl ester (6CI,7CI,8CI);2-Bromoacrylic acid ethyl ester;Ethyl 2-bromoacrylate;Ethyl a-bromoacrylate;NSC 24148;a-Bromoacrylic acid ethyl ester;

Chemical Property of ETHYL 2-BROMOACRYLATE

Chemical Property:

• Vapor Pressure: 2.88mmHg at 25°C
• Refractive Index: 1.471
• Boiling Point: 156.5 °C at 760 mmHg
• Flash Point: 52.2 °C
• PSA: 26.30000
• Density: 1.554g/cm³
• LogP: 1.45810

Purity/Quality:

99% ^*data from raw suppliers

Ethyl2-Bromoacrylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYL 2-BROMOACRYLATE

There total 14 articles about ETHYL 2-BROMOACRYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2,3-dibromopropionic acid ethyl ester (3674-13-3) → 2-bromo-acrylic acid ethyl ester (5459-35-8)

Guidance literature:

With triethylamine; In acetone; at 20 ℃; for 0.5h;

DOI:10.1021/acs.joc.8b02012

Reference yield:

octane (111-65-9) + ketene diethyl acetal (2678-54-8) + tert-butyl alcohol (75-65-0) + 1,1-dibromomethane (74-95-3) → ethyl bromide (74-96-4) + 2-bromo-acrylic acid ethyl ester (5459-35-8)

Guidance literature:

Erhitzen des Reaktonsprodulkts unter 31 Torr;

DOI:10.1021/ja01519a070

Reference yield:

→ 2-bromo-acrylic acid ethyl ester (5459-35-8)

Guidance literature:

With methanol; bromine; at 10 ℃; Behandeln des Reaktionsgemisches mit wss.NaHCO₃-Loesung bei 0-5grad;

upstream raw materials:

octane

ketene diethyl acetal

tert-butyl alcohol

1,1-dibromomethane

Downstream raw materials:

(2R,4R,5R)-2-Methyl-5-phenyl-1-aza-bicyclo[2.1.0]pentane-2,4-dicarboxylic acid 4-ethyl ester 2-methyl ester

5-Oxo-1-phenyl-pyrrolidine-2,4-dicarboxylic acid 2-ethyl ester 4-methyl ester

5-trifluoromethyl-2H-pyrazole-3-carboxylic acid ethyl ester

cyclopropane-1,1,2-tricarboxylic acid triethyl ester