1H-Indole, 2-ethyl-1-(phenylsulfonyl)-

Base Information

Chemical Name:1H-Indole, 2-ethyl-1-(phenylsulfonyl)-
CAS No.:68051-21-8
Molecular Formula:C16H15NO2S
Molecular Weight:285.367
Hs Code.:
DSSTox Substance ID:DTXSID10434271
Nikkaji Number:J3.124.108A
Wikidata:Q82248629

Synonyms:1H-Indole, 2-ethyl-1-(phenylsulfonyl)-;68051-21-8;1-(benzenesulfonyl)-2-ethylindole;2-ethyl-1-(phenylsulfonyl)-1H-indole;SCHEMBL549089;DTXSID10434271;2-ethyl-1-(phenylsulfonyl)indole;VPDZNHPKKFWMJA-UHFFFAOYSA-N;1-Phenylsulfonyl-2-ethyl-1H-indole;1-benzenesulphonyl-2-ethyl-1H-indole

Suppliers and Price of 1H-Indole, 2-ethyl-1-(phenylsulfonyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1H-Indole, 2-ethyl-1-(phenylsulfonyl)-

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:285.08234989
Heavy Atom Count:20
Complexity:422

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=CC2=CC=CC=C2N1S(=O)(=O)C3=CC=CC=C3

Technology Process of 1H-Indole, 2-ethyl-1-(phenylsulfonyl)-

There total 7 articles about 1H-Indole, 2-ethyl-1-(phenylsulfonyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 117966-22-0
(1-phenylsulfonyl-1H-indol-2-yl)ethanone

: 68051-21-8
2-ethyl-1-(phenylsulfonyl)-1H-indole

Guidance literature:: With aluminium trichloride; borane tert-butylamine; In dichloromethane;
DOI:10.1021/jo00279a023

Reference yield: 63.0%

: 40899-71-6
1-benzenesulfonylindole

: 75-03-6
ethyl iodide

: 68051-21-8
2-ethyl-1-(phenylsulfonyl)-1H-indole

Guidance literature:: 1-benzenesulfonylindole; With sec.-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

ethyl iodide; In tetrahydrofuran; hexane; at -78 - 20 ℃; Inert atmosphere;
DOI:10.3390/molecules25020261

Reference yield:

: 40899-71-6
1-benzenesulfonylindole

: 68051-21-8
2-ethyl-1-(phenylsulfonyl)-1H-indole

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) lithium diisopropylamide / 1.) hexane, THF, -70 deg C, 1.5 h, 2.) from -75 deg C to RT, overnight

2: 86 percent / aluminum chloride / CH₂Cl₂ / 1 h

3: 71 percent / AlCl₃, borane-tert-butylamine complex / CH₂Cl₂

With aluminium trichloride; borane tert-butylamine; lithium diisopropyl amide; In dichloromethane;
DOI:10.1021/jo00279a023