4-Chloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxy-5-nitrobenzamide

Base Information

Chemical Name:4-Chloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxy-5-nitrobenzamide
CAS No.:68255-78-7
Molecular Formula:C15H20ClN3O4
Molecular Weight:341.794
Hs Code.:
DSSTox Substance ID:DTXSID201153549

Synonyms:SCHEMBL11086299;DTXSID201153549;4-Chloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxy-5-nitrobenzamide;68255-78-7

Suppliers and Price of 4-Chloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxy-5-nitrobenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 0 raw suppliers

Chemical Property of 4-Chloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxy-5-nitrobenzamide

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:341.1142338
Heavy Atom Count:23
Complexity:431

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCN1CCCC1CNC(=O)C2=CC(=C(C=C2OC)Cl)[N+](=O)[O-]

Technology Process of 4-Chloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxy-5-nitrobenzamide

There total 4 articles about 4-Chloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxy-5-nitrobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 26116-12-1
1-ethyl-2-pyrrolidinemethanamine

: 68255-77-6
2-methoxy-4-chloro-5-nitrobenzoic acid

: 144-55-8
sodium hydrogencarbonate

: 68255-78-7
N-<(1-ethyl-2-pyrrolidinyl)methyl>-2-methoxy-4-chloro-5-nitrobenzamide

Guidance literature:: With thionyl chloride; triethylamine; In dichloromethane; benzene;

Reference yield:

: 68255-77-6
2-methoxy-4-chloro-5-nitrobenzoic acid

: 68255-78-7
N-<(1-ethyl-2-pyrrolidinyl)methyl>-2-methoxy-4-chloro-5-nitrobenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / 0.5 h / Heating

2: Et₃N / CH₂Cl₂ / 0.25 h / Ambient temperature

With thionyl chloride; triethylamine; In dichloromethane;
DOI:10.1021/jm00375a009