2-(Tert-butyl)-5-nitropyrimidin-4-amine

Base Information

Chemical Name:2-(Tert-butyl)-5-nitropyrimidin-4-amine
CAS No.:70227-51-9
Molecular Formula:C₈H₁₂N₄O₂
Molecular Weight:196.209
Hs Code.:
DSSTox Substance ID:DTXSID701250170
Mol file:70227-51-9.mol

Synonyms:2-(TERT-BUTYL)-5-NITROPYRIMIDIN-4-AMINE;70227-51-9;2-tert-butyl-5-nitropyrimidin-4-amine;SCHEMBL12590879;DTXSID701250170;SB56694;2-(1,1-Dimethylethyl)-5-nitro-4-pyrimidinamine

Suppliers and Price of 2-(Tert-butyl)-5-nitropyrimidin-4-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(tert-Butyl)-5-nitropyrimidin-4-amine 95+%
1g
$ 1238.00

Chemenu
2-(tert-Butyl)-5-nitropyrimidin-4-amine 95%
1g
$ 1166.00

Alichem
2-(Tert-butyl)-5-nitropyrimidin-4-amine
1g
$ 1326.13

Alichem
2-(Tert-butyl)-5-nitropyrimidin-4-amine
250mg
$ 519.75

Total 3 raw suppliers

Chemical Property of 2-(Tert-butyl)-5-nitropyrimidin-4-amine

Chemical Property:

PSA：97.62000
LogP:2.36890
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:196.09602564
Heavy Atom Count:14
Complexity:220

Purity/Quality:

99% ^*data from raw suppliers

2-(tert-Butyl)-5-nitropyrimidin-4-amine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)C1=NC=C(C(=N1)N)[N+](=O)[O-]

Technology Process of 2-(Tert-butyl)-5-nitropyrimidin-4-amine

There total 5 articles about 2-(Tert-butyl)-5-nitropyrimidin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 70227-50-8
4-chloro-5-nitro-2-t-butylpyrimidine

: 70227-51-9
4-amino-5-nitro-2-t-butylpyrimidine

Guidance literature:: With ammonia; In methanol; water;

Reference yield:

: 18202-73-8
pivalamidine hydrochloride

: 70227-51-9
4-amino-5-nitro-2-t-butylpyrimidine

Guidance literature:: Multi-step reaction with 4 steps

1: 86 percent / aq. NaOH / Ambient temperature; overnight

2: 92 percent / KNO₃, H₂SO₄ conc. / 8 h / 115 °C

3: POCl₃ / 1) reflux, 3 h, 2) RT, overnight

4: aq. NH₃ / 0 deg C - RT

With ammonium hydroxide; sodium hydroxide; sulfuric acid; potassium nitrate; trichlorophosphate;

Reference yield:

: 42351-88-2
2-t-butyl-3,4-dihydro-4-oxopyrimidine

: 70227-51-9
4-amino-5-nitro-2-t-butylpyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: 92 percent / KNO₃, H₂SO₄ conc. / 8 h / 115 °C

2: POCl₃ / 1) reflux, 3 h, 2) RT, overnight

3: aq. NH₃ / 0 deg C - RT

With ammonium hydroxide; sulfuric acid; potassium nitrate; trichlorophosphate;