N-BOC-4-BENZYL-4-PIPERIDINECARBOXYLIC METHYL ESTER

Base Information

Chemical Name:N-BOC-4-BENZYL-4-PIPERIDINECARBOXYLIC METHYL ESTER
CAS No.:741687-06-9
Molecular Formula:C19H27NO4
Molecular Weight:333.428
Hs Code.:
Mol file:741687-06-9.mol

Synonyms:4-Benzyl-piperidine;4-benzylpiperazine;4-benzylpyperidine;4-benzylpiperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-methyl ester;1-tert-butyl 4-methyl 4-benzylpiperidine-1,4-dicarboxylate;Piperidine,4-benzyl;methyl 1-tert-butoxycarbonyl-4-phenylmethyl-piperidine-4-carboxylate;

Suppliers and Price of N-BOC-4-BENZYL-4-PIPERIDINECARBOXYLIC METHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-BOC-4-(PHENYLMETHYL)-4-PIPERIDINECARBOXYLIC ACID METHYL ESTER 95.00%
5MG
$ 499.42

Total 4 raw suppliers

Chemical Property of N-BOC-4-BENZYL-4-PIPERIDINECARBOXYLIC METHYL ESTER

Chemical Property:

PSA：55.84000
LogP:3.35730

Purity/Quality:

97% ^*data from raw suppliers

1-BOC-4-(PHENYLMETHYL)-4-PIPERIDINECARBOXYLIC ACID METHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-BOC-4-BENZYL-4-PIPERIDINECARBOXYLIC METHYL ESTER

There total 3 articles about N-BOC-4-BENZYL-4-PIPERIDINECARBOXYLIC METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 67-56-1
methanol

: 167263-11-8
N-tert-butyloxycarbonyl-4-benzylpiperidine-4-carboxylic acid

: 741687-06-9
1-tert-butyl 4-methyl 4-benzylpiperidine-1,4-dicarboxylate

Guidance literature:: With diazomethyl-trimethyl-silane; In hexanes; benzene; at 20 ℃; for 4h;

Reference yield: 87.3%

: 124443-68-1
1-tert-Butyl 4-methyl piperidine-1,4-dicarboxylate

: 100-39-0
benzyl bromide

: 741687-06-9
1-tert-butyl 4-methyl 4-benzylpiperidine-1,4-dicarboxylate

Guidance literature:: 1-tert-Butyl 4-methyl piperidine-1,4-dicarboxylate; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 1.5h;

benzyl bromide; In tetrahydrofuran; hexane; at -78 ℃; for 2.5h;
DOI:10.1016/j.ejmech.2010.03.003

Reference yield: 63.0%

: 100-39-0
benzyl bromide

: 741687-06-9
1-tert-butyl 4-methyl 4-benzylpiperidine-1,4-dicarboxylate

Guidance literature:: 1-tert-Butyl 4-methyl piperidine-1,4-dicarboxylate; With lithium diisopropyl amide; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexanes; at -78 ℃; for 1h;

benzyl bromide; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexanes; at 20 ℃; for 20h;