4,5,6,7-Tetrabromo-N,N-dimethyl-1H-benzimidazol-2-amine

Base Information

Chemical Name:4,5,6,7-Tetrabromo-N,N-dimethyl-1H-benzimidazol-2-amine
CAS No.:749234-11-5
Molecular Formula:C₉H₇Br₄N₃
Molecular Weight:476.791
Hs Code.:
European Community (EC) Number:636-153-0
DSSTox Substance ID:DTXSID70416119
Nikkaji Number:J2.656.511A
Wikidata:Q27095459
Metabolomics Workbench ID:149152
ChEMBL ID:CHEMBL376505
Mol file:749234-11-5.mol

Synonyms:2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole;4,5,6,7-tetrabromo-2-(dimethylamino)-1H-benzimidazole;DMAT cpd

Suppliers and Price of 4,5,6,7-Tetrabromo-N,N-dimethyl-1H-benzimidazol-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
DMAT(CK2Inhibitor) >98%
1 g
$ 1200.00

DC Chemicals
DMAT(CK2Inhibitor) >98%
250 mg
$ 600.00

DC Chemicals
DMAT(CK2Inhibitor) >98%
100 mg
$ 300.00

Crysdot
DMAT 98+%
10mg
$ 52.00

Crysdot
DMAT 98+%
50mg
$ 186.00

ChemScene
DMAT 98.03%
50mg
$ 343.00

ChemScene
DMAT 98.03%
10mg
$ 96.00

Cayman Chemical
DMAT ≥98%
1mg
$ 29.00

Cayman Chemical
DMAT ≥98%
5mg
$ 131.00

Cayman Chemical
DMAT ≥98%
10mg
$ 232.00

Total 11 raw suppliers

Chemical Property of 4,5,6,7-Tetrabromo-N,N-dimethyl-1H-benzimidazol-2-amine

Chemical Property:

Vapor Pressure:4.85E-10mmHg at 25°C
Melting Point:>330℃ (Decomposition)
PSA：31.92000
LogP:4.67890
Solubility.:≥23.85 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
XLogP3:4.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:476.73325
Heavy Atom Count:16
Complexity:265

Purity/Quality:

97% ^*data from raw suppliers

DMAT(CK2Inhibitor) >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C1=NC2=C(N1)C(=C(C(=C2Br)Br)Br)Br
Description DMAT is a cell-permeable inhibitor of casein kinase 2 (CK2; IC50 = 0.13 μM). It also inhibits Pim-1, Pim-3, HIPK2, and HIPK3 (IC50s = 0.15, 0.097, 0.37, and 0.59 μM, respectively). DMAT blocks cell growth and induces cell death in cancer cells, both in culture and in mouse xenografts.
Uses 2-Dimethylamino-4,5,6,7-tetrabromobenzimidazole is a novel powerful and selective inhibitor of protein kinase CK2.

Technology Process of 4,5,6,7-Tetrabromo-N,N-dimethyl-1H-benzimidazol-2-amine

There total 1 articles about 4,5,6,7-Tetrabromo-N,N-dimethyl-1H-benzimidazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%