2-(2-Iodophenyl)-N,N-dimethylacetamide

Base Information

Chemical Name:2-(2-Iodophenyl)-N,N-dimethylacetamide
CAS No.:75117-26-9
Molecular Formula:C10H12INO
Molecular Weight:289.116
Hs Code.:
DSSTox Substance ID:DTXSID00512274
Nikkaji Number:J3.551.927K
Wikidata:Q82371449

Synonyms:2-(2-Iodophenyl)-N,N-dimethylacetamide;75117-26-9;N,N-dimethyl-2-iodophenylacetamide;Benzeneacetamide, 2-iodo-N,N-dimethyl-;starbld0019394;SCHEMBL3827620;DTXSID00512274;BPDRJYYNQKBYBG-UHFFFAOYSA-N;A897793;A1-05223

Suppliers and Price of 2-(2-Iodophenyl)-N,N-dimethylacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-(2-Iodophenyl)-N,N-dimethylacetamide

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:288.99636
Heavy Atom Count:13
Complexity:182

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C(=O)CC1=CC=CC=C1I

Technology Process of 2-(2-Iodophenyl)-N,N-dimethylacetamide

There total 5 articles about 2-(2-Iodophenyl)-N,N-dimethylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 62300-07-6
o-iodophenylacetyl chloride

: 124-40-3
dimethyl amine

: 75117-26-9
N,N-dimethyl-2-(2-vinylphenyl)acetamide

Guidance literature:: In dichloromethane; at 0 ℃;
DOI:10.1016/j.tetlet.2012.06.013

Reference yield: 94.0%

: 18698-96-9
o-iodophenylacetic acid

: 506-59-2
N,N-dimethylammonium chloride

: 75117-26-9
N,N-dimethyl-2-(2-vinylphenyl)acetamide

Guidance literature:: With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In acetonitrile; for 15h;
DOI:10.1021/jm010257n

Reference yield:

: 18698-96-9
o-iodophenylacetic acid

: 75117-26-9
N,N-dimethyl-2-(2-vinylphenyl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl chloride; DMF / CH₂Cl₂ / 2 h / 20 °C

2: 0.46 g / CH₂Cl₂; H₂O / 1 h / 0 °C

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; water;
DOI:10.1021/jm030891w