4-(2,2,2-Trifluoroethoxy)benzaldehyde

Base Information

Chemical Name:4-(2,2,2-Trifluoroethoxy)benzaldehyde
CAS No.:76579-46-9
Molecular Formula:C9H7F3O2
Molecular Weight:204.149
Hs Code.:2912490090
European Community (EC) Number:822-768-3
Nikkaji Number:J3.497.403I
Mol file:76579-46-9.mol

Synonyms:4-(2,2,2-trifluoroethoxy)benzaldehyde;76579-46-9;4-(2,2,2-trifluoroethoxy)-benzaldehyde;4-trifluoroethoxybenzaldehyde;SCHEMBL245370;BDA57946;AKOS000196289;p-(2,2,2-trifluoroethoxy)benzaldehyde;4-(2,2,2-trifluoroethoxyl)benzaldehyde;4-(2,2,2-Trifluoro-ethoxy)-benzaldehyde;CS-0434703;EN300-40892;C78450;A1-02143;Z295452586

Suppliers and Price of 4-(2,2,2-Trifluoroethoxy)benzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(2,2,2-trifluoroethoxy)benzaldehyde
250mg
$ 310.00

Acrotein
4-(2,2,2-Trifluoroethoxy)-benzaldehyde 97%
1g
$ 220.00

A1 Biochem Labs
4-(2,2,2-Trifluoroethoxy)-benzaldehyde 95%
5 g
$ 500.00

Total 4 raw suppliers

Chemical Property of 4-(2,2,2-Trifluoroethoxy)benzaldehyde

Chemical Property:

Boiling Point:82 - 85 °C (0.3 mmHg)
PSA：26.30000
LogP:2.44020
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:204.03981395
Heavy Atom Count:14
Complexity:183

Purity/Quality:

99% ^*data from raw suppliers

4-(2,2,2-trifluoroethoxy)benzaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C=O)OCC(F)(F)F

Technology Process of 4-(2,2,2-Trifluoroethoxy)benzaldehyde

There total 12 articles about 4-(2,2,2-Trifluoroethoxy)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 75-89-8
2,2,2-trifluoroethanol

: 1122-91-4
4-bromo-benzaldehyde

: 76579-46-9
4-(2,2,2-trifluoroethoxy)benzaldehyde

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; caesium carbonate; johnphos; In toluene; at 85 ℃; for 1.5h; Reagent/catalyst; Temperature; Catalytic behavior; Inert atmosphere;
DOI:10.1016/j.tet.2015.08.071

Reference yield: 75.0%

: 353-83-3
1,1,1-trifluoro-2-iodoethane

: 123-08-0,65581-83-1
4-hydroxy-benzaldehyde

: 76579-46-9
4-(2,2,2-trifluoroethoxy)benzaldehyde

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.1c01674

Reference yield: 71.0%

: C₈H₈BF₁₂O₄^(1-)*Na⁽¹⁺⁾

: 104-88-1
4-chlorobenzaldehyde

: 76579-46-9
4-(2,2,2-trifluoroethoxy)benzaldehyde

Guidance literature:: 4-chlorobenzaldehyde; With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tert-butyl XPhos; In tert-Amyl alcohol; at 20 ℃; for 0.0833333h; Inert atmosphere;

C₈H₈BF₁₂O₄^(1-)*Na⁽¹⁺⁾; In tert-Amyl alcohol; at 100 ℃; for 1h; Inert atmosphere;
DOI:10.1002/chem.201704205