353-83-3

Basic information

• Product Name: 2-Iodo-1,1,1-trifluoroethane
• Synonyms: 1H,1H-Perfluoroethyl iodide;CF3CH2I;Ethane, 1,1,1-trifluoro-2-iodo-;2-IODO-1,1,1-TRIFLUOROETHANE;1-IODO-2,2,2-TRIFLUOROETHANE;2,2,2-TRIFLUOROETHYL IODIDE;1,1,1-TRIFLUORO-2-IODOETHANE;TRIFLUORO IODOETHANE
• CAS NO: 353-83-3
• Molecular Formula: C₂H₂F₃I
• Molecular Weight: 209.94
• EINECS: 206-541-0
• Product Categories: organofluorine compounds
• Mol File: 353-83-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 54.8 °C(lit.)
• Flash Point: 53-55°C
• Appearance: Clear colorless to pink/Liquid
• Density: 2.13 g/mL at 25 °C(lit.)
• Vapor Pressure: 3.96 psi ( 20 °C)
• Refractive Index: n20/D 1.401(lit.)
• Storage Temp.: Keep Cold
• Solubility: Chloroform
• Water Solubility: Insoluble
• Sensitive: Light Sensitive
• BRN: 1733201
• CAS DataBase Reference: 2-Iodo-1,1,1-trifluoroethane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Iodo-1,1,1-trifluoroethane(353-83-3)
• EPA Substance Registry System: 2-Iodo-1,1,1-trifluoroethane(353-83-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-37/39
• WGK Germany: 3
• F: 8
• HazardClass: IRRITANT
• Hazardous Substances Data: 353-83-3(Hazardous Substances Data)

Usage

Uses

1,1,1-Trifluoro-2-iodoethane (cas# 353-83-3) is a compound useful in organic synthesis.

Chemical Properties

clear colorless to pink liquid

Synthesis Reference(s)

Tetrahedron Letters, 34, p. 4241, 1993 DOI: 10.1016/S0040-4039(00)60538-5

InChI:InChI=1/C2H2F3I/c3-2(4,5)1-6/h1H2

Synthetic route

1-styrenyloxytrimethylsilane (13735-81-4) + 1-[hydroxy(tosyloxy)iodo]-1H,1H-perfluoroethane (166903-46-4) → 1,1,1-trifluoro-2-iodoethane (353-83-3) + 1-phenyl-2-(p-tolylsulfonyloxy)ethanone (7257-94-5)

Conditions	Yield
In dichloromethane for 1h; Ambient temperature;	A n/a B 58%

1-(Trimethylsilyloxy)cyclohexene (6651-36-1) + 1-[hydroxy(tosyloxy)iodo]-1H,1H-perfluoroethane (166903-46-4) → 1,1,1-trifluoro-2-iodoethane (353-83-3) + 2-(tosyloxy)cyclohexanone (81447-34-9)

Conditions	Yield
In dichloromethane at 0℃; for 3h;	A n/a B 56%

1,1,1-trifluoro-2-chloroethane (75-88-7) → 1,1,1-trifluoro-2-iodoethane (353-83-3)

Conditions	Yield
With potassium bromide at 300℃; for 0.333333h;	36%

tris(2,2,2-trifluoroethyl) phosphate (358-63-4) → 1,1,1-trifluoro-2-iodoethane (353-83-3)

Conditions	Yield
With Pentaethylene glycol; sodium iodide

1-bromo-1,1-difluoro-2-iodoethane (420-93-9) → 1,1,1-trifluoro-2-iodoethane (353-83-3) + Vinylidene fluoride (75-38-7)

Conditions	Yield
With mercury(I) fluoride at 140℃;

2,2,2-trifluorodiazoethane (371-67-5) → 1,1,1-trifluoro-2-iodoethane (353-83-3)

Conditions	Yield
With hydrogen iodide; toluene at -75℃;

2,2,2-Trifluoroethyl p-toluenesulfonate (433-06-7) → 1,1,1-trifluoro-2-iodoethane (353-83-3)

Conditions	Yield
With sodium iodide; diethylene glycol

Iodoacetic acid (64-69-7) → 1,1,1-trifluoro-2-iodoethane (353-83-3) + bis-(1,1-difluoro-2-iodo-ethyl) ether (51100-31-3)

Conditions	Yield
With sulfur tetrafluoride at 60℃; for 3h;
With sulfur tetrafluoride at 26℃; for 21h;

diiodomethane (75-11-6) + metyhyl chlorodifluoroacetate (1514-87-0) → 1,1,1-trifluoro-2-iodoethane (353-83-3)

Conditions	Yield
With potassium fluoride; copper(l) iodide; cadmium(II) iodide In N,N,N,N,N,N-hexamethylphosphoric triamide at 120℃; for 8h;	78 % Turnov.

1,1,1-trifluoro-2-chloroethane (75-88-7) → chloroethylene (75-01-4) + 1,1,1-trifluoro-2-iodoethane (353-83-3) + 1-Chloro-2,2-difluoroethene (359-10-4) + Hexafluoroethane (76-16-4) + 1,1,2-trifluoroethylene (359-11-5) + 1,2-dichloro-ethane (107-06-2)

Conditions	Yield
Rate constant; Thermodynamic data; Ambient temperature; Irradiation; Eo;

C20H17F3OP(1+)*I(1-) → 1,1,1-trifluoro-2-iodoethane (353-83-3)

Conditions	Yield
In solid at 160 - 190℃; Yield given;

2,2,2-trifluorodiazoethane (371-67-5) + hydrogen iodide (10034-85-2) + toluene (108-88-3) → 1,1,1-trifluoro-2-iodoethane (353-83-3)

Conditions	Yield
at -75℃;

2,2,2-trifluoroethanol (75-89-8) + iodine (7553-56-2) + red phosphorus → 1,1,1-trifluoro-2-iodoethane (353-83-3)

1-bromo-1,1-difluoro-2-iodoethane (420-93-9) + mercury (I)-fluoride → 1,1,1-trifluoro-2-iodoethane (353-83-3) + Vinylidene fluoride (75-38-7)

Conditions	Yield
at 140℃;

trans-bis(dimethylglyoximato)(CH2CF3)(4-cyanopyridine)cobalt(III) + iodine (7553-56-2) → {CoI(NC5H4(CN))(NOC(CH3)C(CH3)NOH)2} + 1,1,1-trifluoro-2-iodoethane (353-83-3)

Conditions	Yield
In benzene Kinetics; iodinolysis with I2 in benzene soln. at 305 K;

1,1,1-trifluoro-2-iodoethane (353-83-3) + trifluoroacetic anhydride (407-25-0) → (2,2,2-trifluoroethyl)-λ3-iodanediyl bis(2,2,2-trifluoroacetate) (100422-04-6)

Conditions	Yield
Stage #1: trifluoroacetic anhydride With dihydrogen peroxide; trifluoroacetic acid In water at 0℃; for 0.0833333h; Stage #2: 1,1,1-trifluoro-2-iodoethane at 0 - 20℃;	100%
Stage #1: trifluoroacetic anhydride With dihydrogen peroxide at 0℃; for 0.166667h; Inert atmosphere; Stage #2: 1,1,1-trifluoro-2-iodoethane at 0 - 22℃; for 24h; Inert atmosphere;	90%
Stage #1: trifluoroacetic anhydride With dihydrogen peroxide; trifluoroacetic acid In water at 0℃; for 0.0833333h; Inert atmosphere; Stage #2: 1,1,1-trifluoro-2-iodoethane In water at 0 - 20℃; for 20h; Inert atmosphere;

1,1,1-trifluoro-2-iodoethane (353-83-3) + trifluoroacetic acid (76-05-1) + trifluoroacetic anhydride (407-25-0) → (2,2,2-trifluoroethyl)-λ3-iodanediyl bis(2,2,2-trifluoroacetate) (100422-04-6)

Conditions	Yield
Stage #1: trifluoroacetic acid; trifluoroacetic anhydride With dihydrogen peroxide In water at 0℃; for 0.0833333h; Stage #2: 1,1,1-trifluoro-2-iodoethane In water at 0 - 20℃; for 20h;	100%
In water; dihydrogen peroxide at 0 - 20℃;	40%

5-amino-4-fluoro-2-methylbenzene-1-thiol (885028-69-3) + 1,1,1-trifluoro-2-iodoethane (353-83-3) → 2-fluoro-4-methyl-5-[(2,2,2-trifluoroethyl)sulfanyl]phenylamine

Conditions	Yield
With rongalite; potassium hydroxide In N,N-dimethyl-formamide at 20℃; for 2h;	99%
With rongalite; potassium hydroxide In N,N-dimethyl-formamide at 20℃; for 2h;	99%
With rongalite; potassium hydroxide In N,N-dimethyl-formamide at 20℃; for 2h;	99%

1,1,1-trifluoro-2-iodoethane (353-83-3) + (2,6-bis[(di-tert-butylphosphino)methyl]phenyl)rhodium dinitrogen (219832-01-6) → Rh(I)(CH2CF3)(2,6-(CH2P(t)Bu2)2C6H3) (230636-00-7)

Conditions	Yield
In benzene-d6 inert atmosphere; 1-4 equiv. of CF3CH2I, room temp.; evapn.; NMR-spectroscopy;	99%

dimethyl(N,N,N',N',-tetramethylethanediamine)platinum + 1,1,1-trifluoro-2-iodoethane (353-83-3) → trans-Pt(N,N,N',N'-tetramethylethylenediamine)(CH2CF3)(CH3)2I (660390-90-9, 660417-21-0)

Conditions	Yield
In toluene (N2); CF3CH2I added to a suspn. of Pt complex at -78°C, stirred for ca. 10 min; evapd. (vac., below 0°C);	99%

1,1,1-trifluoro-2-iodoethane (353-83-3) + trifluoroprop-1-yn-1-ylxenonium(II) tetrafluoroborate (663152-74-7) → trifluoroprop-1-yn-1-yl(2,2,2-trifluoroethyl)iodonium tetrafluoroborate

Conditions	Yield
With hydrogen fluoride at -20 - 15℃; for 1h; Inert atmosphere;	99%
In hydrogen fluoride byproducts: Xe; HF (liquid); soln. of CF3CCXe(BF4) (-20°C) in anhyd. HF added to stirred neat CF3CH2I (-20°C), stirred at 15°C for 1 h; volatiles evapd., residue washed (CH2Cl2, 5°C), dried (vac.); (1)H, (13)C, (19)F NMR;	99%

2-(3-chloro-pyridin-2-yl)-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylic acid ethyl ester (500011-95-0) + 1,1,1-trifluoro-2-iodoethane (353-83-3) → ethyl 1-(3-chloro-2-pyridinyl)-3-(2,2,2-trifluoroethoxy)-1H-pyrazole-5-carboxylate

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 100℃;	99%
With potassium carbonate In N,N-dimethyl-formamide at 100℃;

2-(3-chloro-pyridin-2-yl)-5-oxo-pyrazolidine-3-carboxylic acid ethyl ester (500011-88-1) + 1,1,1-trifluoro-2-iodoethane (353-83-3) → ethyl 1-(3-chloro-2-pyridinyl)-3-(2,2,2-trifluoroethoxy)-1H-pyrazole-5-carboxylate

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 3h;	99%

1,1,1-trifluoro-2-iodoethane (353-83-3) + para-iodoanisole (696-62-8) → (2,2,2-trifluoroethyl) (4-methoxyphenyl) sulfide (130612-75-8)

Conditions	Yield
With sulfur; sodium tetrahydroborate; 1,10-Phenanthroline; [(1,10-phenanthroline)Cu(μ-SCH2CF3)]2 In N,N-dimethyl-formamide at 90℃; for 12h; Kinetics; Reagent/catalyst; Temperature; Solvent; Inert atmosphere; Sealed tube;	99%
With sodium tetrahydroborate; 1,10-Phenanthroline; iodine; sulfur In N,N-dimethyl-formamide at 80℃; for 16h; Inert atmosphere;	84%

p-nitrobenzene iodide (636-98-6) + 1,1,1-trifluoro-2-iodoethane (353-83-3) → (4-nitrophenyl)(2,2,2-trifluoroethyl)sulfane

Conditions	Yield
With sodium tetrahydroborate; 1,10-Phenanthroline; iodine; sulfur In N,N-dimethyl-formamide at 80℃; for 16h; Inert atmosphere;	99%
With sulfur; sodium tetrahydroborate; copper(l) iodide; 1,10-Phenanthroline In N,N-dimethyl-formamide at 85℃; for 12h; Inert atmosphere; Sealed tube;	99%

1,1,1-trifluoro-2-iodoethane (353-83-3) + para-nitrophenyl bromide (586-78-7) → (4-nitrophenyl)(2,2,2-trifluoroethyl)sulfane

Conditions	Yield
With sodium tetrahydroborate; 1,10-Phenanthroline; iodine; sulfur In N,N-dimethyl-formamide at 95℃; for 1h; Inert atmosphere;	99%
With sulfur; sodium tetrahydroborate; copper(l) iodide; dimedone In N,N-dimethyl-formamide at 95℃; for 12h; Inert atmosphere; Sealed tube;	96%

1,1,1-trifluoro-2-iodoethane (353-83-3) + 2-iodo-5-nitrotoluene (5326-38-5) → (2-methyl-4-nitrophenyl)(2,2,2-trifluoroethyl)sulfane

Conditions	Yield
With sulfur; sodium tetrahydroborate; copper(l) iodide; 1,10-Phenanthroline In N,N-dimethyl-formamide at 85℃; for 12h; Inert atmosphere; Sealed tube;	99%

1,1,1-trifluoro-2-iodoethane (353-83-3) + 4-iodobenzoic acid ethyl ester (51934-41-9) → ethyl 4-((2,2,2-trifluoroethyl)thio)benzoate

Conditions	Yield
With sulfur; sodium tetrahydroborate; copper(l) iodide; 1,10-Phenanthroline In N,N-dimethyl-formamide at 85℃; for 12h; Inert atmosphere; Sealed tube;	99%

1,1,1-trifluoro-2-iodoethane (353-83-3) + 1-Fluoro-3-iodobenzene (1121-86-4) → (2,2,2-trifluoroethyl) (3-fluorophenyl) sulfide (62158-90-1)

Conditions	Yield
With sulfur; sodium tetrahydroborate; copper(l) iodide; 1,10-Phenanthroline In N,N-dimethyl-formamide at 85℃; for 12h; Inert atmosphere; Sealed tube;	99%

1,1,1-trifluoro-2-iodoethane (353-83-3) + 2-iodo-9H-fluorene (2523-42-4) → (9H-fluoren-2-yl)(2,2,2-trifluoroethyl)selane

Conditions	Yield
With potassium hexafluorophosphate; selenium; sodium tetrahydroborate; copper(l) iodide; 1,10-Phenanthroline In N,N-dimethyl-formamide at 95℃; for 16h; Sealed tube;	99%

4-iododibenzo[b,d]thiophene (132034-89-0) + 1,1,1-trifluoro-2-iodoethane (353-83-3) → 4-(2,2,2-trifluoroethyl)dibenzo[b,d]thiophene (1360594-83-7)

Conditions	Yield
With nickel(II) iodide; 1,1'-bis-(diphenylphosphino)ferrocene; manganese; 4,4'-di-tert-butyl-2,2'-bipyridine In N,N-dimethyl acetamide at 80℃; for 24h; Inert atmosphere; Sealed tube;	99%

1,1,1-trifluoro-2-iodoethane (353-83-3) + trifluoroacetic anhydride (407-25-0) → (2,2,2-trifluoroethyl)-λ3-iodanediyl bis(2,2,2-trifluoroacetate) (100422-04-6) + trifluoroacetic acid (76-05-1)

Conditions	Yield
With dihydrogen peroxide at -15 - 20℃; for 72h;	A 98% B n/a

1,1,1-trifluoro-2-iodoethane (353-83-3) + 2-iodobenzonitrile (4387-36-4) → 2-((2,2,2-trifluoroethyl)selanyl)benzonitrile

Conditions	Yield
With potassium hexafluorophosphate; selenium; sodium tetrahydroborate; copper(l) iodide; 1,10-Phenanthroline In N,N-dimethyl-formamide at 95℃; for 16h; Sealed tube;	98%
With selenium; sodium tetrahydroborate; copper(l) iodide; 1,10-Phenanthroline In N,N-dimethyl-formamide at 95℃; for 16h; Inert atmosphere;	98%

1,1,1-trifluoro-2-iodoethane (353-83-3) + 8-bromo-2-phenyl-4H-pyrazolo[1,5-a]quinazolin-5-one → 8-bromo-2-phenyl-4-(2,2,2-trifluoro-ethyl)-4H-pyrazolo[1,5-a]quinazolin-5-one

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 150℃; for 0.166667h; Cooling with ice; Microwave irradiation;	97%
Stage #1: 8-bromo-2-phenyl-4H-pyrazolo[1,5-a]quinazolin-5-one With sodium hydride In N,N-dimethyl-formamide; mineral oil for 0.25h; Cooling with ice; Stage #2: 1,1,1-trifluoro-2-iodoethane In N,N-dimethyl-formamide; mineral oil at 150℃; for 0.0833333h; Cooling with ice; Microwave irradiation;	97%

1,1,1-trifluoro-2-iodoethane (353-83-3) + 1-isoquinolone (491-30-5) → 2-(2,2,2-trifluoroethyl)isoquinolin-1(2H)-one

Conditions	Yield
With caesium carbonate In N,N-dimethyl-formamide at 50℃; for 3h;	97%

1,1,1-trifluoro-2-iodoethane (353-83-3) + 2-iodobiphenyl (2113-51-1) → [1,1′-biphenyl]-2-yl(2,2,2-trifluoroethyl)sulfane

Conditions	Yield
With sulfur; sodium tetrahydroborate; copper(l) iodide; 1,10-Phenanthroline In N,N-dimethyl-formamide at 85℃; for 12h; Inert atmosphere; Sealed tube;	97%

1,1,1-trifluoro-2-iodoethane (353-83-3) + 3'-iodoacetophenone (14452-30-3) → 1-(3-((2,2,2-trifluoroethyl)thio)phenyl)ethanone

Conditions	Yield
With sulfur; sodium tetrahydroborate; copper(l) iodide; 1,10-Phenanthroline In N,N-dimethyl-formamide at 85℃; for 12h; Inert atmosphere; Sealed tube;	97%

1,1,1-trifluoro-2-iodoethane (353-83-3) + 3-methoxy-1-iodobenzene (766-85-8) → (3-methoxyphenyl)(2,2,2-trifluoroethyl)selane

Conditions	Yield
With potassium hexafluorophosphate; selenium; sodium tetrahydroborate; copper(l) iodide; 1,10-Phenanthroline In N,N-dimethyl-formamide at 95℃; for 16h; Catalytic behavior; Reagent/catalyst; Temperature; Sealed tube;	97%

1,1,1-trifluoro-2-iodoethane (353-83-3) + p-(iodophenyl)carboxaldehyde (15164-44-0) → 4-(2,2,2-trifluoroethyl)benzaldehyde

Conditions	Yield
With nickel(II) iodide; 1,1'-bis-(diphenylphosphino)ferrocene; manganese; 4,4'-di-tert-butyl-2,2'-bipyridine In N,N-dimethyl acetamide at 80℃; for 24h; Inert atmosphere; Sealed tube;	96%
With copper In dimethyl sulfoxide at 120℃; for 55h; Schlenk technique; Inert atmosphere; Sealed tube;	63%

1,1,1-trifluoro-2-iodoethane (353-83-3) + 2-bromo-9H-fluorene (1133-80-8) → (9H-fluoren-2-yl)(2,2,2-trifluoroethyl)selane

Conditions	Yield
With potassium hexafluorophosphate; selenium; sodium tetrahydroborate; copper(l) iodide; 1,10-Phenanthroline In N,N-dimethyl-formamide at 95℃; for 16h; Sealed tube;	96%

1,1,1-trifluoro-2-iodoethane (353-83-3) + 2-hydroxy-3,17β-bis(benzyloxy)estra-1,3,5(10)-triene (159143-75-6) → 2-(2',2',2'-Trifluoroethoxy)-3,17β-Dibenzyloxyestra-1,3,5(10)-Triene (192062-06-9)

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide a) 110 deg C, 3 h, b) 130 deg C, 2 h;	95%

9-(prop-2-yn-1-yl)-9H-carbazole (4282-77-3) + 1,1,1-trifluoro-2-iodoethane (353-83-3) → 9-(5,5,5-trifluoropent-2-ynyl)-9,9a-dihydro-4aH-carbazole

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane; tris-(dibenzylideneacetone)dipalladium(0); bis[2-(diphenylphosphino)phenyl] ether In toluene at 80℃; for 24h; Inert atmosphere; Schlenk technique;	95%

1,1,1-trifluoro-2-iodoethane (353-83-3) + methyl 3-iodo-benzoate (618-91-7) → methyl 3-((2,2,2-trifluoroethyl)thio)benzoate (647856-12-0)

Conditions	Yield
With sulfur; sodium tetrahydroborate; copper(l) iodide; 1,10-Phenanthroline In N,N-dimethyl-formamide at 85℃; for 12h; Inert atmosphere; Sealed tube;	95%

1,1,1-trifluoro-2-iodoethane (353-83-3) + 2-(4-bromophenyl)acrylic acid (28131-17-1) → 1-(4'-bromophenyl)-4,4,4-trifluoro-1-butanone (1180670-65-8)

Conditions	Yield
With tert.-butylhydroperoxide; copper acetylacetonate; silver sulfate; triethylamine In water; acetonitrile at 80℃; for 0.5h; Sealed tube; Microwave irradiation;	95%

1,1,1-trifluoro-2-iodoethane (353-83-3) + 2-[4-(4-iodobenzoyl)phenoxy]-2-methylpropanoic acid isopropyl ester (1383569-21-8) → isopropyl 2-methyl-2-(4-(4-(2,2,2-trifluoroethyl)benzoyl)phenoxy)propanoate

Conditions	Yield
With nickel(II) iodide; 1,1'-bis-(diphenylphosphino)ferrocene; manganese; 4,4'-di-tert-butyl-2,2'-bipyridine In N,N-dimethyl acetamide at 80℃; for 24h; Inert atmosphere; Sealed tube;	95%

Upstream product

• 420-93-9 1-bromo-1,1-difluoro-2-iodoethane 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 166903-46-4 1-[hydroxy(tosyloxy)iodo]-1H,1H-perfluoroethane 
• 371-67-5 2,2,2-trifluorodiazoethane 
• 10034-85-2 hydrogen iodide 
• 108-88-3 toluene 
• 75-89-8 2,2,2-trifluoroethanol 
• 7553-56-2 iodine 
• 75-88-7 1,1,1-trifluoro-2-chloroethane 
• 6651-36-1 1-(Trimethylsilyloxy)cyclohexene 
• 75-11-6 diiodomethane 
• 1514-87-0 metyhyl chlorodifluoroacetate 
• 64-69-7 Iodoacetic acid 
• 433-06-7 2,2,2-Trifluoroethyl p-toluenesulfonate 

Downstream Products

• 2262-07-9 2,2,2-trifluoroethyl phenyl sulfide 
• 75-38-7 Vinylidene fluoride 
• 128651-00-3 phenyl 2,2,2-trifluoroethyl telluride 
• 128651-01-4 1-Methyl-4-(2,2,2-trifluoro-ethyltellanyl)-benzene 
• 599-94-0 1,2-bis(phenylsulfonyl)ethane 
• 50616-99-4 9,9'-dimethoxy-9,9'-bifluorene 
• 3248-58-6 2,2,2-trifluoroethyl 
• 60375-88-4 4-((E)-4,4,4-trifluorobut-1-ene-1-yl)benzene 
• 138445-32-6 1-phenyl-1-(4,4,4-trifluoro-1-iodobutyl)silacyclobutane 
• 90330-30-6 2,6-Di-tert-butyl-4-[5-methyl-2-(2,2,2-trifluoro-ethylsulfanyl)-1H-imidazol-4-yl]-phenol 
• 103343-09-5 1,3-Dihydro-5-(2-fluorophenyl)-3(R)-(3'-indolyl)methyl-1-(2,2,2-trifluoroethyl)-2H-1,4-benzodiazepin-2-one 
• 23199-54-4 2,3-dihydro-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-1H-benzo[e][1,4]diazepine 
• 57328-25-3 diphenyl(2,2,2-trifluoroethyl)phosphine oxide 

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