Cyclopentanecarboxylic acid, phenylmethyl ester

Base Information

• Chemical Name: Cyclopentanecarboxylic acid, phenylmethyl ester
• CAS No.: 78277-22-2
• Molecular Formula: C13H16O2
• Molecular Weight: 204.269
• Mol file: 78277-22-2.mol

Synonyms:Cyclopentanecarboxylic acid benzyl ester;Cyclopentancarbonsaeure-benzylester;benzyl cyclopentanecarboxylate;

Chemical Property of Cyclopentanecarboxylic acid, phenylmethyl ester

Chemical Property:

• Boiling Point: 130 °C (5 mmHg)
• PSA: 26.30000
• LogP: 2.92000

Purity/Quality:

benzylcyclopentanecarboxylate 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclopentanecarboxylic acid, phenylmethyl ester

There total 4 articles about Cyclopentanecarboxylic acid, phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

Cyclopentane (287-92-3) + carbon monoxide (201230-82-2) + benzyl alcohol (100-51-6,185532-71-2) → cyclopentanecarboxylic acid benzyl ester (78277-22-2)

Guidance literature:

With di-tert-butyl peroxide; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; palladium dichloride; In 1,2-dichloro-ethane; at 110 ℃; for 24h; under 3800.26 Torr; Autoclave;

DOI:10.1002/chem.201602791

Reference yield: 69.0%

Cyclopentanecarboxylic acid chloride (4524-93-0) + benzyl alcohol (100-51-6,185532-71-2) → cyclopentanecarboxylic acid benzyl ester (78277-22-2)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 4h;

DOI:10.1021/ol702892e

Reference yield:

cyclopentanecarboxylic acid (3400-45-1) + benzyl bromide (100-39-0) → cyclopentanecarboxylic acid benzyl ester (78277-22-2)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 18h;

upstream raw materials:

2-Chlorocyclohexanone

Cyclopentanecarboxylic acid chloride

benzyl alcohol

cyclopentanecarboxylic acid

Downstream raw materials:

1-allyl-cyclopentanecarboxylic acid benzyl ester

propan-2-yl 3-{[4-(3-{1-[(benzyloxy)carbonyl]cyclopentyl}prop-1-yn-1-yl)phenyl]carbonyl}-2-ethylindolizine-7-carboxylate

benzyl 1-(prop-2-yn-1-yl)cyclopentanecarboxylate

1-{3-[4-({2-ethyl-7-[(propan-2-yloxy)carbonyl]indolizine-3-yl}carbonyl)phenyl]propyl}cyclopentane carboxylic acid