Triethyl(4-tert-butylcyclohexyloxy)silane

Base Information

• Chemical Name: Triethyl(4-tert-butylcyclohexyloxy)silane
• CAS No.: 81256-40-8
• Molecular Formula: C16H34OSi
• Molecular Weight: 270.531
• DSSTox Substance ID: DTXSID001182736
• Nikkaji Number: J1.396.886A,J1.396.887J,J506.647F
• Mol file: 81256-40-8.mol

Synonyms:SCHEMBL9355205;DTXSID001182736;Triethyl(4-tert-butylcyclohexyloxy)silane;1alpha-(Triethylsiloxy)-4alpha-tert-butylcyclohexane;1alpha-(Triethylsiloxy)-4beta-tert-butylcyclohexane;trans-1-(1,1-Dimethylethyl)-4-[(triethylsilyl)oxy]cyclohexane;81256-40-8

Chemical Property of Triethyl(4-tert-butylcyclohexyloxy)silane

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 6
• Exact Mass: 270.237892238
• Heavy Atom Count: 18
• Complexity: 224

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC[Si](CC)(CC)OC1CCC(CC1)C(C)(C)C

Technology Process of Triethyl(4-tert-butylcyclohexyloxy)silane

There total 7 articles about Triethyl(4-tert-butylcyclohexyloxy)silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

triethylsilyl chloride (994-30-9) + 4-t-butylcyclohexyl formate (68039-42-9) → cis,trans-<(4-tert-butylcyclohexyl)oxy>triethylsilane (81256-40-8,81256-47-5,134863-01-7)

Guidance literature:

With samarium diiodide; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; at 20 ℃; for 0.0833333h;

DOI:10.1080/00397919908085960

Reference yield: 96.0%

triethylsilane (617-86-7) + 4-tercbutyl-cyclohexanone (98-53-3) → cis,trans-<(4-tert-butylcyclohexyl)oxy>triethylsilane (81256-40-8,81256-47-5,134863-01-7)

Guidance literature:

With silver trifluoroacetate; tris(triphenylphosphine)ruthenium(II) chloride; In toluene; at 110 ℃; for 20h;

DOI:10.1021/jo00133a045

Reference yield: 95.0%

triethylsilane (617-86-7) + trans-4-tert-butylcyclohexanol methyl ether (15876-31-0) → (4-tert-Butyl-cyclohexyloxy)-triethyl-silane (81256-40-8)

Guidance literature:

With (η4-1,5-cyclooctadiene)bis(triphenylphosphine)iridium tetrakis[3,5-bis(trifluoromethyl)phenyl]borate; In dichloromethane-d2; at 50 ℃; for 2h; Reagent/catalyst;

DOI:10.1021/acscatal.0c01718

upstream raw materials:

triethylsilane

4-tercbutyl-cyclohexanone

triethylsilyl chloride

4-t-butylcyclohexyl formate

Downstream raw materials:

trans-4-tert-butylcyclohexanol

4-(1,1-dimethylethyl)-cyclohexanol