D-Guluronic Acid

Base Information

Chemical Name:D-Guluronic Acid
CAS No.:15769-56-9
Molecular Formula:C₆H₁₀O₇
Molecular Weight:194.141
Hs Code.:
European Community (EC) Number:239-860-9
Metabolomics Workbench ID:155982
Wikipedia:Guluronic_acid
Mol file:15769-56-9.mol

Synonyms:alpha-L-guluronic acid;G2013;G2013 compound;guluronic acid;guluronic acid, (alpha-L)-isomer;guluronic acid, (L)-isomer;guluronic acid, sodium salt, (L)-isomer

Suppliers and Price of D-Guluronic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 22 raw suppliers

Chemical Property of D-Guluronic Acid

Chemical Property:

Vapor Pressure:1.49E-14mmHg at 25°C
Boiling Point:553.4°Cat760mmHg
Flash Point:302.6°C
PSA：0.00000
Density:1.748g/cm³
LogP:0.00000
XLogP3:-2.3
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:1
Exact Mass:194.04265265
Heavy Atom Count:13
Complexity:205

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1(C(C(OC(C1O)O)C(=O)O)O)O
Isomeric SMILES:[C@H]1([C@H]([C@H](OC([C@@H]1O)O)C(=O)O)O)O
Description Glucuronic acid is a sugar acid derived from glucose, with its sixth carbon atom oxidized to a carboxylic acid. In living beings, this primary oxidation occurs with UDP-α-D-glucose (UDPG), not with the free sugar. Glucuronic acid, like its precursor glucose, can exist as a linear (carboxo-)aldohexose (<1%), or as a cyclic hemiacetal (furanose or pyranose). Aldohexoses such as D-glucose are capable of forming two furanose forms (α and β) and two pyranose forms (α and β). By the Fischer convention, glucuronic acid has two stereoisomers (enantiomers), D- and L-glucuronic acid, depending on its configuration at C-5. Most physiological sugars are of the D-configuration. Due to ring closure, cyclic sugars have another asymmetric carbon atom (C-1), resulting in two more stereoisomers, named anomers. Depending on the configuration at C-1, there are two anomers of glucuronic acid, α- and β-form. In β-D-glucuronic acid the C-1 hydroxy group is on the same side of the pyranose ring as the carboxyl group. In the free sugar acid, the β-form is prevalent (~64%), whereas in the organism, the α-form UDP-α-D-glucuronic acid (UDPGA) predominates.

Technology Process of D-Guluronic Acid

There total 18 articles about D-Guluronic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 20513-98-8
1,2-O-isopropylidene-α-D-glucofuranurono-6,3-lactone

: 576-37-4,685-73-4,1986-14-7,1986-15-8,2073-35-0,3402-98-0,6556-12-3,6814-36-4,14982-50-4,15769-56-9,21675-50-3,21675-51-4,21675-52-5,21675-53-6,27766-62-7,28223-51-0,28223-52-1,39737-41-2,70332-45-5,84710-57-6,102681-51-6,108729-78-8,25249-06-3,25990-10-7,36562-70-6,36655-86-4
D-galacturonic acid

Guidance literature:: With acidic cationen-exchanger; water;
DOI:10.1021/ja01614a072

Reference yield:

[GlcA-Rha]20[IdoA-Rha]6[GlcA-Rha-Xyl]6GlcA₂₆Glc₄[SO₃-]30: [GlcA-Rha]20[IdoA-Rha]6[GlcA-Rha-Xyl]6GlcA₂₆Glc₄[SO₃-]30

: 58-86-6
D-xylose

: 3615-41-6,478518-52-4
L-Rhamnose

: 50-99-7
D-glucose

: 6556-12-3,25249-06-3,25990-10-7,36562-70-6,36655-86-4
D-Glucuronic acid

: 576-37-4,685-73-4,1986-14-7,1986-15-8,2073-35-0,3402-98-0,6556-12-3,6814-36-4,14982-50-4,15769-56-9,21675-50-3,21675-51-4,21675-52-5,21675-53-6,27766-62-7,28223-51-0,28223-52-1,39737-41-2,70332-45-5,84710-57-6,102681-51-6,108729-78-8,25249-06-3,25990-10-7,36562-70-6,36655-86-4
D-galacturonic acid

Guidance literature:: [GlcA-Rha]20[IdoA-Rha]6[GlcA-Rha-Xyl]6GlcA₂₆Glc₄[SO₃-]30; With water; trifluoroacetic acid; at 120 ℃; for 0.75h;

With Helix pomatia β-glucuronidase; at 37 ℃; for 16h; pH=5; aq. acetate buffer; Enzymatic reaction;
DOI:10.1016/j.carbpol.2011.12.041

Reference yield:

[GlcA-Rha]25[IdoA-Rha]6[GlcA-Rha-Xyl]4GlcA₂₄Glc₂[SO₃-]32: [GlcA-Rha]25[IdoA-Rha]6[GlcA-Rha-Xyl]4GlcA₂₄Glc₂[SO₃-]32

: 58-86-6
D-xylose

: 3615-41-6,478518-52-4
L-Rhamnose

: 50-99-7
D-glucose

: 6556-12-3,25249-06-3,25990-10-7,36562-70-6,36655-86-4
D-Glucuronic acid

: 576-37-4,685-73-4,1986-14-7,1986-15-8,2073-35-0,3402-98-0,6556-12-3,6814-36-4,14982-50-4,15769-56-9,21675-50-3,21675-51-4,21675-52-5,21675-53-6,27766-62-7,28223-51-0,28223-52-1,39737-41-2,70332-45-5,84710-57-6,102681-51-6,108729-78-8,25249-06-3,25990-10-7,36562-70-6,36655-86-4
D-galacturonic acid

Guidance literature:: [GlcA-Rha]25[IdoA-Rha]6[GlcA-Rha-Xyl]4GlcA₂₄Glc₂[SO₃-]32; With water; trifluoroacetic acid; at 120 ℃; for 0.75h;

With Helix pomatia β-glucuronidase; at 37 ℃; for 16h; pH=5; aq. acetate buffer; Enzymatic reaction;
DOI:10.1016/j.carbpol.2011.12.041