(Aminomethyl)trimethylsilane

Base Information

• Chemical Name: (Aminomethyl)trimethylsilane
• CAS No.: 18166-02-4
• Molecular Formula: C4H13NSi
• Molecular Weight: 103.239
• Hs Code.: 2931900090
• European Community (EC) Number: 242-049-2
• NSC Number: 96778
• UNII: Y4CS778E5B
• DSSTox Substance ID: DTXSID30171176
• Nikkaji Number: J260.904E
• Wikidata: Q23638225
• ChEMBL ID: CHEMBL76074
• Mol file: 18166-02-4.mol

Synonyms:(Aminomethyl)trimethylsilane;18166-02-4;(Trimethylsilyl)methylamine;trimethylsilylmethanamine;(trimethylsilyl)methanamine;aminomethyltrimethylsilane;1-(Trimethylsilyl)methylamine;Trimethylsilylmethylamine;Methanamine, 1-(trimethylsilyl)-;1-(trimethylsilyl)methanamine;Y4CS778E5B;EINECS 242-049-2;NSC-96778;NSC96778;AMTMS;aminomethyl trimethylsilane;1-aminomethyltrimethylsilane;UNII-Y4CS778E5B;CHEMBL76074;SCHEMBL433960;DTXSID30171176;Methylamine, 1-(trimethylsilyl)-,;MFCD00042931;NSC 96778;STL373559;AKOS006220480;AT37252;FT-0659042;(Trimethylsilyl)methylamine, >=98.0% (GC);EN300-142767;J-011612;Q23638225

Chemical Property of (Aminomethyl)trimethylsilane

Chemical Property:

• Vapor Pressure: 149mmHg at 25°C
• Melting Point: <0 °C
• Refractive Index: n20/D 1.416
• Boiling Point: 66.851 °C at 760 mmHg
• PKA: 10.89±0.10(Predicted)
• Flash Point: -5.768 °C
• PSA: 26.02000
• Density: 0.771 g/cm³
• LogP: 1.94110
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 103.081725953
• Heavy Atom Count: 6
• Complexity: 37.3

Purity/Quality:

97% ^*data from raw suppliers

(Trimethylsilyl)methanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F, C
• Hazard Codes: F,C
• Statements: 11-34-37
• Safety Statements: 16-26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C)CN

Technology Process of (Aminomethyl)trimethylsilane

There total 6 articles about (Aminomethyl)trimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

trimethylsilylmethyl azide (87576-94-1) → N-trimethylsilylmethylamine (18166-02-4)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

Reference yield: 76.0%

N-<(Trimethylsilyl)methyl>phthalimide (18042-62-1) → N-trimethylsilylmethylamine (18166-02-4)

Guidance literature:

With hydrazine hydrate;

DOI:10.1016/S0040-4039(99)00744-3

Reference yield: 48.0%

Chloromethyltrimethylsilane (2344-80-1) → N-trimethylsilylmethylamine (18166-02-4)

Guidance literature:

Chloromethyltrimethylsilane; With ammonium hydroxide; In methanol; at 115 ℃; for 16h; under 15514.9 Torr;

With sodium hydroxide; In diethyl ether;

DOI:10.1002/anie.201612235

upstream raw materials:

N-<(Trimethylsilyl)methyl>phthalimide

Chloromethyltrimethylsilane

trimethylsilylmethyl azide

<<(trimethylsilyl)methyl>imino>triphenylphosphorane

Downstream raw materials:

N,N'-bis-(trimethylsilanyl-methyl)-terephthalamide

4-nitro-N-[(trimethylsilyl)methyl]benzamide

N,N'-Bis-(trimethylsilylmethyl)-phthalamid

[N-(trimethylsilyl)methyl]urea