87576-94-1

Basic information

• Product Name: TRIMETHYLSILYLMETHYL AZIDE
• Synonyms: TRIMETHYLSILYLMETHYL AZIDE;AZIDOMETHYLTRIMETHYLSILANE;Silyl Methyl azide triMethyl
• CAS NO: 87576-94-1
• Molecular Formula: C₄H₁₁N₃Si
• Molecular Weight: 129.24
• Product Categories: Amination;Si (Classes of Silicon Compounds);Si-(C)4 Compounds;Silicon Compounds (for Synthesis);Synthetic Organic Chemistry
• Mol File: 87576-94-1.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 92-95°C
• Flash Point: 6°C
• Appearance: /
• Density: 0,87 g/cm3
• Refractive Index: 1.4300 to 1.4340
• Solubility: Sol organic solvents; insol water.
• CAS DataBase Reference: TRIMETHYLSILYLMETHYL AZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: TRIMETHYLSILYLMETHYL AZIDE(87576-94-1)
• EPA Substance Registry System: TRIMETHYLSILYLMETHYL AZIDE(87576-94-1)

Safety Data

• Statements: 11-23/24/25
• Safety Statements: 16-36/37/39-45
• RIDADR: 1992
• HazardClass: 3
• PackingGroup: II
• Hazardous Substances Data: 87576-94-1(Hazardous Substances Data)

Usage

Physical properties

bp 43 °C/43 mmHg; IR νmax 2100 cm?1; 1H NMR (CDCl3) δ = 0.12 (s, 9H), 2.75 (s, 2H); MS m/z 129, 73.

Uses

Trimethylsilylmethyl Azide is used in the amination of organometallic compounds; preparation of heterocyclic compounds; precursor of azomethine ylide, reactant in Silylmethyl-Substituted Heterocumulenes and [3 + 2] Cycloaddition etc.

Preparation

Obtained in high yield by reaction of sodium azide and (chloromethyl)trimethylsilane in DMF or HMPA at 80°C.

Upstream product

• 18243-41-9 (bromomethyl)trimethylsilane 
• 2344-80-1 Chloromethyltrimethylsilane 

Downstream Products

• 93098-41-0 (1S,2R,4S,5R)-3-Trimethylsilanylmethyl-3-aza-tricyclo[3.2.1.0^2,4]octane 
• 87576-92-9 Phenyl-(3-trimethylsilanylmethyl-3H-[1,2,3]triazol-4-yl)-methanone 
• 87576-91-8 Phenyl-(1-trimethylsilanylmethyl-1H-[1,2,3]triazol-4-yl)-methanone 
• 1352807-56-7 4-phenyl-1-((trimethylsilyl)methyl)-1H-1,2,3-triazole 
• 90606-24-9 Cyclohexylidene-trimethylsilanylmethyl-amine 
• 116985-78-5 5-tert-butyl-3-trimethylsilylmethyl-3H-1,2,3,4-triazaphosphole 
• 130231-89-9 5-picrylimino-4-trimethylsilylmethyl-1,2,3,4-thiatriazoline 
• 130217-47-9 [1-{2-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-phenyl}-meth-(E)-ylidene]-trimethylsilanylmethyl-amine 
• 90606-20-5 [(E)-3-Phenyl-prop-2-en-(Z)-ylidene]-trimethylsilanylmethyl-amine 
• 90606-19-2 [(E)-3-Phenyl-prop-2-en-(E)-ylidene]-trimethylsilanylmethyl-amine 
• 50-00-0 formaldehyd 
• 73859-26-4 2-azallyl anion 

Relevant articles and documents

NOVEL TRICYCLIC COMPOUNDS AS ANTICANCER AGENTS

The present invention is directed to tricyclic compounds, pharmaceutically acceptable compositions comprising compounds of the invention and methods of using said compositions in the treatment of various disorders.

TRICYCLIC COMPOUNDS AS ANTICANCER AGENTS

The present invention is directed to tricyclic compounds (I), pharmaceutically acceptable compositions comprising compounds of the invention and methods of using said compositions in the treatment of various disorders.

1,2,3-triazolium ionic liquids

The present invention relates to compositions of matter that are ionic liquids, the compositions comprising substituted 1,2,3-triazolium cations combined with any anion. Compositions of the invention should be useful in the separation of gases and, perhap