diamminedichlorodihydroxyplatinum IV

Base Information

• Chemical Name: diamminedichlorodihydroxyplatinum IV
• CAS No.: 53261-25-9
• Molecular Formula: Cl₂H₈N₂O₂Pt
• Molecular Weight: 334.062
• Mol file: 53261-25-9.mol

Synonyms:Dichlorodihydroxydiammineplatinum

Chemical Property of diamminedichlorodihydroxyplatinum IV

Chemical Property:

• Vapor Pressure: 5990mmHg at 25°C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 92.50000
• Density: g/cm³
• LogP: 1.24230

Purity/Quality:

99% ^*data from raw suppliers

DIAMMINEDICHLORODIHYDROXYPLATINUM IV 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of diamminedichlorodihydroxyplatinum IV

There total 15 articles about diamminedichlorodihydroxyplatinum IV which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

cisplatin (15663-27-1) + dihydrogen peroxide (7722-84-1) → (OC-6-33)-(diammine)dichloridodihydroxidoplatinum(IV) (125074-46-6,31246-62-5,31246-63-6,31246-66-9,53261-25-9)

Guidance literature:

In water; at 60 ℃; for 1h;

DOI:10.1039/c9nj05989j

Reference yield: 95.5%

cisplatine (26035-31-4,14913-33-8,15663-27-1) + dihydrogen peroxide (7722-84-1) → (OC-6-33)-(diammine)dichloridodihydroxidoplatinum(IV) (125074-46-6,31246-62-5,31246-63-6,31246-66-9,53261-25-9)

Guidance literature:

In water; at 70 ℃; for 8h; Temperature; Darkness;

Reference yield: 95.0%

cisplatin (15663-27-1) + water (7732-18-5) + dihydrogen peroxide (7722-84-1) → (OC-6-33)-(diammine)dichloridodihydroxidoplatinum(IV) (125074-46-6,31246-62-5,31246-63-6,31246-66-9,53261-25-9)

Guidance literature:

at 50 ℃; for 1h; Darkness;

DOI:10.1021/acs.molpharmaceut.0c00781

upstream raw materials:

cisplatine

dihydrogen peroxide

cisplatin

water

Refernces

• 1、 -. "Tetravalent veratric acid platinum as well as preparation method and application thereof". Paragraph 0031-0033; 0035-0036; 0038-0039. . Retrieved 2021/06/21.
• 2、 Kong, Qingduo,Wei, Dengshuai,Xie, Peng,Wang, Bin,Yu, Kunyi,Kang, Xiang,Wang, Yongjun. "Photothermal Therapy via NIR II Light Irradiation Enhances DNA Damage and Endoplasmic Reticulum Stress for Efficient Chemotherapy". . . Retrieved 2021/05/21.