Methyl 4-hydroxy-3-methoxy-cinnamate

Base Information

Chemical Name:Methyl 4-hydroxy-3-methoxy-cinnamate
CAS No.:2309-07-1
Molecular Formula:C11H12O4
Molecular Weight:208.214
Hs Code.:2918990090
DSSTox Substance ID:DTXSID801347441
Wikidata:Q104918972
Mol file:2309-07-1.mol

Synonyms:SCHEMBL510492;DTXSID801347441;methyl 3-methoxy-4-hydroxycinnamate;methyl 4-hydroxy-3-methoxy-cinnamate;METHYL-4-HYDROXY-3-METHOXYCINNAMATE;FT-0698057;FT-0772817

Suppliers and Price of Methyl 4-hydroxy-3-methoxy-cinnamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl4-Hydroxy-3-methoxycinnamate
10g
$ 175.00

TRC
FerulicAcidMethylEster
1g
$ 75.00

Matrix Scientific
Methyl 3-(4-hydroxy-3-methoxyphenyl)acrylate 98%
1g
$ 28.00

Matrix Scientific
Methyl 3-(4-hydroxy-3-methoxyphenyl)acrylate 98%
5g
$ 82.00

Matrix Scientific
Methyl 3-(4-hydroxy-3-methoxyphenyl)acrylate 98%
10g
$ 136.00

DC Chemicals
Ferulicacidmethylester >98%
1 g
$ 200.00

DC Chemicals
Ferulicacidmethylester >98%
250 mg
$ 100.00

CSNpharm
MethylFerulate
25mg
$ 35.00

Crysdot
Methyl3-(4-hydroxy-3-methoxyphenyl)acrylate 98%
100g
$ 189.00

ChemScene
Ferulicacidmethylester 99.18%
100g
$ 95.00

Total 78 raw suppliers

Chemical Property of Methyl 4-hydroxy-3-methoxy-cinnamate

Chemical Property:

Vapor Pressure:5.13E-05mmHg at 25°C
Melting Point:62-65 °C
Refractive Index:1.574
Boiling Point:338.077 °C at 760 mmHg
PKA:8.88±0.18(Predicted)
Flash Point:130.409 °C
PSA：55.76000
Density:1.205 g/cm³
LogP:1.58700
Storage Temp.:2-8°C
Solubility.:Acetone (Slightly), Chloroform (Slightly), Ethyl Acetate (Sparingly), Methanol (
Water Solubility.:Slightly soluble in water.
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:208.07355886
Heavy Atom Count:15
Complexity:237

Purity/Quality:

≥98% ^*data from raw suppliers

Methyl4-Hydroxy-3-methoxycinnamate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)C=CC(=O)OC)O
Uses Ferulic acid is a hydroxycinnamic acid that is abundant in plants and originally derived from giant fennel (F. communis). This naturally-occurring phenolic has antioxidant activities that provide protection against inflammation and cancer. Ferulic acid methyl ester is a lipophilic derivative of ferulic acid, demonstrating increased ability to cross cell membranes. Ferulic acid methyl ester has less antioxidant capacity than ferulic acid in neuronal PC12 cells (IC50 = 74.7 μM for ferulic acid ethyl ester vs. 44.6 μM for ferulic acid, 2,2-diphenyl-1-picrylhydrazyl radical scavenging). Ferulic acid methyl ester, at 10-25 μg/ml, inhibits the release of pro-inflammatory cytokines, blocks the expression of COX-2, and reduces nitric oxide generation from LPS-stimulated macrophages. Ferulic Acid Methyl Ester is a derivative of Ferulic Acid (F308900), used as an antioxidant and food preservative. It has less antioxidant capacity than ferulic acid.

Technology Process of Methyl 4-hydroxy-3-methoxy-cinnamate

There total 85 articles about Methyl 4-hydroxy-3-methoxy-cinnamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%