Ethanimidic acid, N-(phenylmethoxy)-, ethyl ester, (E)-

Base Information

• Chemical Name: Ethanimidic acid, N-(phenylmethoxy)-, ethyl ester, (E)-
• CAS No.: 86208-93-7
• Molecular Formula: C11H15NO2
• Molecular Weight: 193.246
• Mol file: 86208-93-7.mol

Synonyms:

Chemical Property of Ethanimidic acid, N-(phenylmethoxy)-, ethyl ester, (E)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ethanimidic acid, N-(phenylmethoxy)-, ethyl ester, (E)-

There total 3 articles about Ethanimidic acid, N-(phenylmethoxy)-, ethyl ester, (E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

O-Ethyl thioacetate (926-67-0) + N-benzyloxyamine (622-33-3) → ethyl (E)-O-benzylacetohydroximate (86208-93-7)

Guidance literature:

In N,N-dimethyl-formamide; at 40 ℃; for 3h;

DOI:10.1055/s-1983-30288

Reference yield: 60.0%

ethyl N-hydroxyacetimidate (20703-41-7) + sodium ethanolate (141-52-6) + benzyl bromide (100-39-0) → ethyl (E)-O-benzylacetohydroximate (86208-93-7)

Guidance literature:

In ethanol; at 50 - 60 ℃; for 62h;

DOI:10.1021/jo00207a017

Reference yield:

N-benzyloxyacetamide (4797-81-3) → ethyl (E)-O-benzylacetohydroximate (86208-93-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 56 percent / thionyl chloride / 4 h / 98 °C

2: 52.3 percent / ethanol / 1.2 h / 66 - 70 °C

With thionyl chloride; In ethanol;

DOI:10.1021/jo00207a017

upstream raw materials:

O-Ethyl thioacetate

N-benzyloxyamine

ethyl N-hydroxyacetimidate

sodium ethanolate

Refernces

• 1、 Brion, Jean-Daniel,Reynaud, Pierre,Kirkiacharian, Serge. "A New Convenient Route to Alkyl Hydroximates and their ON-Alkyl Derivatives (Alkyl N-Hydroxy- and N-Alkoxycarboximidates)". . p. 220 - 222. Retrieved 2007/10/02.