Imidazolidine

Base Information

• Chemical Name: Imidazolidine
• CAS No.: 504-74-5
• Molecular Formula: C3H8 N2
• Molecular Weight: 72.1099
• Hs Code.: 2933290090
• UNII: AEE9PL2D22
• DSSTox Substance ID: DTXSID2073192
• Nikkaji Number: J6.220K
• Wikipedia: Imidazolidine,Dihydroimidazol-2-ylidene
• Wikidata: Q3131185,Q5276431
• Metabolomics Workbench ID: 54829
• Mol file: 504-74-5.mol

Synonyms:Imidazolidine;Imidazolidines

Chemical Property of Imidazolidine

Chemical Property:

• Vapor Pressure: 50.8mmHg at 25°C
• Melting Point: 68.2-68.8 °C
• Boiling Point: 92.8°Cat760mmHg
• PKA: 10.33±0.20(Predicted)
• Flash Point: °C
• PSA: 24.06000
• Density: 0.892g/cm³
• LogP: -0.20570
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: -0.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 72.068748264
• Heavy Atom Count: 5
• Complexity: 24.1

Purity/Quality:

99% ^*data from raw suppliers

Imidazolidine 98 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CNCN1
• Uses: The imidazolines, was discovered at American Cyanamid in the early 1980s. Extensive research has led to the development of four commercial compounds: imazapyr, imazamethabenzmethyl, imazethapyr, and imazaquin. Like the sulfonylureas, the imidazolines are extremely active at low rates.

Technology Process of Imidazolidine

There total 5 articles about Imidazolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + ethylenediamine (107-15-3,85404-18-8) → tetrahydroimidazole (504-74-5)

Guidance literature:

With magnesium sulfate; potassium carbonate; In chloroform; at 20 ℃; for 18h;

Reference yield: 22.0%

endo-3,5-di(p-tolyl)-3,5-diazatricyclo[5.2.1.0]dec-8-ene (1367520-68-0) + ethylenediamine (107-15-3,85404-18-8) → tetrahydroimidazole (504-74-5) + cis-endo-N,N'-di(p-tolyl)bicyclo[2.2.1]hept-5-ene-2,3-diamine (1367903-87-4)

Guidance literature:

With toluene-4-sulfonic acid; at 150 ℃; for 48h;

DOI:10.1080/00397911.2010.537426

Reference yield:

1,3,6,8-tetraazatricyclo[4.4.1.13,8]dodecane (51-46-7) → tetrahydroimidazole (504-74-5) + 1,3,5-triazabicyclo[3.2.1]-octane (280-29-5) + hexamethylenetetramine (100-97-0) + 1,3,6,8-tetraazatricyclo[4.3.1.13,8]undecane (125251-91-4)

Guidance literature:

With ammonium fluoride; In water-d2; at 23 ℃; for 8h; Title compound not separated from byproducts.;

DOI:10.1016/j.tetlet.2008.01.091

upstream raw materials:

formaldehyd

ethylenediamine hydrochloride

ethylenediamine

1,3,6,8-tetraazatricyclo[4.4.1.1^3,8]dodecane

Downstream raw materials:

1,3-dibenzoyl-imidazolidine

1,3,6,8-tetraazatricyclo[4.4.1.1^3,8]dodecane

ethylenediamine

1,3-bis(2-hydroxy-3,5-di-tert-butylbenzyl)imidazolidine

Refernces

• 1、 -. "METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS". Page/Page column 25. . Retrieved 2008/12/07.
• 2、 Coldham,Houdayer,Judkins,Witty. "N,N'-bisacylimidazolidines from 1,2-diamines". . p. 1463 - 1466. Retrieved 2007/10/03.