Bis(p-chlorophenoxy)methane

Base Information

• Chemical Name: Bis(p-chlorophenoxy)methane
• CAS No.: 555-89-5
• Molecular Formula: C13H10 Cl2 O2
• Molecular Weight: 269.127
• European Community (EC) Number: 209-107-9
• NSC Number: 6172
• UNII: 11HJA8FF4I
• DSSTox Substance ID: DTXSID7041673
• Nikkaji Number: J6.476I
• Wikidata: Q27251325
• Mol file: 555-89-5.mol

Synonyms:Bis(p-chlorophenoxy)methane;555-89-5;DCPM;Bis(4-chlorophenoxy)methane;Oxythane;NEOTRAN;Bis-(4-chlorophenoxy)methane;Caswell No. 091;Di-(p-chlorophenoxy)methane;Di-(4-chlorophenoxy)methane;Di-p-chlorodiphenoxymethane;Benzene, 1,1'-(methylenebis(oxy))bis(4-chloro-;Methane, bis(p-chlorophenoxy)-;1-chloro-4-[(4-chlorophenoxy)methoxy]benzene;NSC 6172;EINECS 209-107-9;K 1875;UNII-11HJA8FF4I;BRN 1978248;11HJA8FF4I;AI3-15208;1,1'-(Methylenebis(oxy))bis(4-chloro)benzene;NSC-6172;4-06-00-00833 (Beilstein Handbook Reference);Benzene, 1,1'-[methylenebis(oxy)]bis[4-chloro-;oxy-than;Maybridge4_000167;WLN: GR DO1OR DG;Di-(p-chlorodiphenoxy)methane;SCHEMBL1003652;DTXSID7041673;NSC6172;HMS1521H13;CCG-47883;IDI1_030749;BIS(P-CHLOROPHENOXY)METHANE [MI];LS-89984;FT-0718686;Benzene,1'-[methylenebis(oxy)]bis[4-chloro-;K-1875;SR-01000637472-1;Q27251325

Chemical Property of Bis(p-chlorophenoxy)methane

Chemical Property:

• Vapor Pressure: 4.91E-06mmHg at 25°C
• Melting Point: 70.5℃
• Boiling Point: 393.2oC at 760 mmHg
• Flash Point: 151.5oC
• PSA: 18.46000
• Density: 1.308 g/cm3
• LogP: 4.40870
• XLogP3: 4.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 268.0057849
• Heavy Atom Count: 17
• Complexity: 188

Purity/Quality:

99% ^*data from raw suppliers

BIS-(4-CHLOROPHENOXY)METHANE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1OCOC2=CC=C(C=C2)Cl)Cl

Technology Process of Bis(p-chlorophenoxy)methane

There total 8 articles about Bis(p-chlorophenoxy)methane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

dichloromethane (75-09-2) + 4-chloro-phenol (106-48-9,82344-39-6) → bis(p-chlorophenoxy)methane (555-89-5)

Guidance literature:

With potassium hydroxide; benzyltrimethylammonium chloride; In water; at 40 ℃; for 72h;

DOI:10.1246/cl.1988.1773

Reference yield: 91.0%

dichloromethane (75-09-2) + potassium 4-chlorophenoxide (1121-74-0) → bis(p-chlorophenoxy)methane (555-89-5)

Guidance literature:

With poly(ethylene glycol)-600 (PEG-600); for 24.5h; Ambient temperature;

Reference yield: 90.0%

dichloromethane (75-09-2) + sodium 4-chlorophenolate (1193-00-6) → bis(p-chlorophenoxy)methane (555-89-5)

Guidance literature:

With 1-n-butyl-3-methylimidazolim bromide; at 60 ℃; for 2.5h;

DOI:10.1080/00397910500281267

upstream raw materials:

dichloromethane

sodium 4-chlorophenolate

diiodomethane

4-chloro-phenol

Downstream raw materials:

Bis-(4-Chlor-Phenoxy)-Methylchlorid

Dichlorobis(4-chlorophenoxy)methane

Refernces

• 1、 Liu, Wenming,Szewczyk, Joanna,Waykole, Liladhar,Repic, Oljan,Blacklock, Thomas J.. "Practical synthesis of diaryloxymethanes". . p. 1751 - 1754. Retrieved 2007/10/03.
• 2、 Khalafi-Nezhad,Soltani Rad,Hakimelahi,Mokhtari. "One step synthesis of imidazole and benzimidazole acycloaromatic nucleoside analogs". . p. 10341 - 10344. Retrieved 2007/10/03.