Diphenyl(p-tolyl)methanol

Base Information

• Chemical Name: Diphenyl(p-tolyl)methanol
• CAS No.: 5440-76-6
• Molecular Formula: C20H18 O
• Molecular Weight: 274.362
• Hs Code.: 2902909090
• NSC Number: 20741
• DSSTox Substance ID: DTXSID10202790
• Nikkaji Number: J504.941E
• Wikidata: Q63399106
• Mol file: 5440-76-6.mol

Synonyms:4-methyltriphenylcarbinol;4-methyltrityl-OH

Chemical Property of Diphenyl(p-tolyl)methanol

Chemical Property:

• Vapor Pressure: 3.8E-08mmHg at 25°C
• Melting Point: 77.5-78.5 °C
• Boiling Point: 429.7°Cat760mmHg
• PKA: 12.87±0.29(Predicted)
• Flash Point: 170.7°C
• PSA: 20.23000
• Density: 1.112g/cm³
• LogP: 4.27920
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 274.135765193
• Heavy Atom Count: 21
• Complexity: 286

Purity/Quality:

99% ^*data from raw suppliers

Diphenyl(p-tolyl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)O

Technology Process of Diphenyl(p-tolyl)methanol

There total 36 articles about Diphenyl(p-tolyl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-methyl-benzoic acid methyl ester (99-75-2) + phenyllithium (591-51-5) → (4-methylphenyl)diphenylmethanol (5440-76-6)

Guidance literature:

In water; at 25 ℃; for 0.00555556h; Solvent;

DOI:10.1016/j.tet.2020.131898

Reference yield: 87.0%

benzophenone (119-61-9) + para-bromotoluene (106-38-7) → (4-methylphenyl)diphenylmethanol (5440-76-6)

Guidance literature:

para-bromotoluene; With magnesium; In tetrahydrofuran; Reflux;

benzophenone; In tetrahydrofuran; at 20 ℃; Reflux;

DOI:10.1002/chem.200902669

Reference yield: 84.0%

4-methyl-benzoic acid methyl ester (99-75-2) + bromobenzene (108-86-1,52753-63-6) → (4-methylphenyl)diphenylmethanol (5440-76-6)

Guidance literature:

bromobenzene; With magnesium; In tetrahydrofuran; at 20 ℃; for 1h;

4-methyl-benzoic acid methyl ester; In tetrahydrofuran; at 50 ℃; for 5h;

DOI:10.1016/j.tet.2005.05.012

upstream raw materials:

tetrachloromethane

benzophenone

di(p-tolyl)zinc

tri-(4-methylphenyl)aluminum

Downstream raw materials:

4-(diphenylhydroxymethyl)benzoic acid

[4-(bromomethyl)phenyl](diphenyl)methanol

diphenyl-p-tolylmethylamine

1,2,3,4-tetraphenylnaphthalene

Refernces

• 1、 Muoz-Gmez, Jose-Luis,Marn-Montesinos, Ildefonso,Lloveras, Vega,Pons, Miquel,Vidal-Gancedo, Jos,Veciana, Jaume. "Novel PTM-TEMPO biradical for fast dissolution dynamic nuclear polarization". . p. 5402 - 5405. Retrieved 2014.
• 2、 Quivelli, Andrea F.,D'Addato, Giovanna,Vitale, Paola,García-álvarez, Joaquín,Perna, Filippo M.,Capriati, Vito. "Expeditious and practical synthesis of tertiary alcohols from esters enabled by highly polarized organometallic compounds under aerobic conditions in Deep Eutectic Solvents or bulk water". . . Retrieved 2021/01/18.
• 3、 Lloveras, Vega,Liko, Flonja,Mu?oz-Gómez, José L.,Veciana, Jaume,Vidal-Gancedo, José. "Redox-Active PTM Radical Dendrimers as Promising Multifunctional Molecular Switches". . p. 9400 - 9412. Retrieved 2019/11/21.