Dodecanamide

Base Information

• Chemical Name: Dodecanamide
• CAS No.: 1120-16-7
• Deprecated CAS: 8014-77-5
• Molecular Formula: C12H25NO
• Molecular Weight: 199.337
• Hs Code.: 2924199090
• European Community (EC) Number: 214-298-7
• NSC Number: 26630,889
• UNII: 3BD22052MO
• DSSTox Substance ID: DTXSID5022146
• Nikkaji Number: J43.223G
• Wikidata: Q27116246
• Metabolomics Workbench ID: 4491
• Mol file: 1120-16-7.mol

Synonyms:DODECANAMIDE;Lauramide;1120-16-7;Dodecylamide;Lauric amide;Lauryl amide;Dodecamide;Amide KK;Lauric acid amide;Dodecanoic acid amide;NSC 889;EINECS 214-298-7;NSC 26630;UNII-3BD22052MO;NSC-889;3BD22052MO;NSC-26630;Lauroylamide;n-dodecanamide;Dodecylacid amide;Diamide Y;LAURAMIDE [INCI];SCHEMBL42192;NSC889;DTXSID5022146;SCHEMBL11355406;CHEBI:34726;BAA12016;NSC26630;LMFA08010001;MFCD00025532;AKOS006228958;FS-4114;LS-184906;CS-0206349;FT-0625579;L0077;D91239;A925590;Q27116246

Chemical Property of Dodecanamide

Chemical Property:

• Appearance/Colour: solid
• Vapor Pressure: 0.000122mmHg at 25°C
• Melting Point: 99 °C
• Refractive Index: 1.45
• Boiling Point: 335.12 °C at 760 mmHg
• PKA: 16.62±0.40(Predicted)
• Flash Point: 156.475 °C
• PSA: 43.09000
• Density: 0.877 g/cm³
• LogP: 4.09290
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility.: Insoluble in water
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 10
• Exact Mass: 199.193614421
• Heavy Atom Count: 14
• Complexity: 134

Purity/Quality:

98%,99%, ^*data from raw suppliers

Lauramide >96.0%(GC) ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCCCCCCCCCCC(=O)N

Technology Process of Dodecanamide

There total 34 articles about Dodecanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

undecyl cyanide (2437-25-4) → lauric acid amide (1120-16-7)

Guidance literature:

With dihydrogen peroxide; hexadecyltrimethylammonium methanesulfonate; sodium hydroxide; In water; at 25 ℃; for 1h;

DOI:10.2174/157017809787582708

Reference yield: 92.0%

Lauroyl azide (43009-32-1) → lauric acid amide (1120-16-7)

Guidance literature:

With zinc(II) tetrahydroborate; In 1,2-dimethoxyethane; for 0.5h; Ambient temperature;

DOI:10.1021/jo00094a021

Reference yield: 89.0%

Dodecanal (112-54-9) → lauric acid (143-07-7) + lauric acid amide (1120-16-7) + undecyl cyanide (2437-25-4)

Guidance literature:

With H₂SO₄*2NH₂OH; Rh(OH)x/Al₂O₃; In water; for 9h; Heating;

DOI:10.1002/anie.200701273

upstream raw materials:

lauric acid

n-dodecanoyl chloride

ethyl laurate

urea

Downstream raw materials:

N-dodecanoylglycine

N-lauryl iminodiacetic acid

undecylammonium p-toluenesulfonate

ethyl laurate

Refernces

• 1、 Ma, Xiaoyun,Lu, Ming. "Copper(II) acetate-catalysed conversion of aldoximes to amides under mild conditions". . p. 594 - 596. Retrieved 2016.
• 2、 Chatterjee, Basujit,Jena, Soumyashree,Chugh, Vishal,Weyhermüller, Thomas,Werlé, Christophe. "A Molecular Iron-Based System for Divergent Bond Activation: Controlling the Reactivity of Aldehydes". . p. 7176 - 7185. Retrieved 2021/06/30.
• 3、 Marchetti, Piera M.,Richardson, Shona M.,Kariem, Noor M.,Campopiano, Dominic J.. "Synthesis of: N-acyl amide natural products using a versatile adenylating biocatalyst". supporting information. p. 1192 - 1196. Retrieved 2019/07/31.