CYCLOPENTYLACETONE

Base Information

• Chemical Name: CYCLOPENTYLACETONE
• CAS No.: 1122-98-1
• Molecular Formula: C8H14O
• Molecular Weight: 126.199
• Hs Code.: 2914299000
• Mol file: 1122-98-1.mol

Synonyms:2-Propanone,cyclopentyl- (6CI,7CI);1-Cyclopentyl-2-propanone;3-Cyclopentylpropanone;Cyclopentyl-2-propanone;Cyclopentylacetone;NSC 60396;

Chemical Property of CYCLOPENTYLACETONE

Chemical Property:

• Vapor Pressure: 1.786mmHg at 25°C
• Refractive Index: 1.442
• Boiling Point: 166.418 °C at 760 mmHg
• Flash Point: 54.235 °C
• PSA: 17.07000
• Density: 0.902 g/cm³
• LogP: 2.15570

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Cyclopentylpropan-2-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1-Cyclopentylpropan-2-one is a reagent that is used in the synthesis of Cyclopentamine which is a vasoconstrictor that acts as a releasing agent of the neurotransmitters norepinephrine, epinephrine and dopamine.

Technology Process of CYCLOPENTYLACETONE

There total 14 articles about CYCLOPENTYLACETONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

Cyclopentane (287-92-3) + percarbonate de O,O-tert-butyle et O-isopropyle (65700-06-3) → 1-cyclopentyl-propan-2-one (1122-98-1) + bicyclopentyl (1636-39-1) + 2,5-hexanedione (110-13-4) + tert-butyl alcohol (75-65-0)

Guidance literature:

at 130 ℃; for 2.5h; Further byproducts given;

DOI:10.1016/0040-4020(82)80049-5

Reference yield: 32.0%

acetone (67-64-1) + cyclopentene (142-29-0) → 1-cyclopentyl-propan-2-one (1122-98-1)

Guidance literature:

acetone; With potassium acetate; magnesium(II) acetate tetrahydrate; In acetic anhydride; at 70 ℃; Inert atmosphere;

cyclopentene; With potassium permanganate; In acetic anhydride; at 70 ℃; Inert atmosphere;

DOI:10.1021/jo902321f

Reference yield:

prop-2-yn-1-ylcyclopentane (116279-08-4) → 1-cyclopentyl-propan-2-one (1122-98-1)

Guidance literature:

prop-2-yn-1-ylcyclopentane; With 2,6-dimethylaniline; bis(trimethylsilyl)acetylenetitanocene; In toluene; at 85 ℃; for 24h;

With hydrogenchloride;

DOI:10.1002/chem.200305674

upstream raw materials:

1-cyclopentenylpropan-2-one

1-cyclopentylidenepropan-2-one

2-cyclopentylacetonitrile

ethyl 4-cyclopentyl-3-oxobutanoate

Downstream raw materials:

2-cyclopentyl-1-methyl-ethylamine

piperdinium acetate

Methylspiro<2.4>hept-1-ylketon

1-(3-cyclopentylprop-2-yl)-2,4-dioxo-3-isocyananto-5-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine