Cyclopentamine

Base Information

• Chemical Name: Cyclopentamine
• CAS No.: 102-45-4
• Molecular Formula: C9H19 N
• Molecular Weight: 141.257
• Hs Code.: 2921300090
• UNII: WB9Q6M8O60
• DSSTox Substance ID: DTXSID60861710
• Nikkaji Number: J5.008C
• Wikipedia: Cyclopentamine
• Wikidata: Q15408414
• NCI Thesaurus Code: C81341
• Metabolomics Workbench ID: 152073
• ChEMBL ID: CHEMBL329203
• Mol file: 102-45-4.mol

Synonyms:cyclopentadrine;cyclopentamine

Chemical Property of Cyclopentamine

Chemical Property:

• Vapor Pressure: 1.37mmHg at 25°C
• Refractive Index: 1.4920 (estimate)
• Boiling Point: 171.8°Cat760mmHg
• PKA: pKa 11.47 (Uncertain)
• Flash Point: 45.5°C
• PSA: 12.03000
• Density: 0.838g/cm³
• LogP: 2.56550
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 141.151749610
• Heavy Atom Count: 10
• Complexity: 84.7

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Cyclopentyl-N-methylpropan-2-amine 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CC1CCCC1)NC
• Therapeutic Function: Vasoconstrictor

Technology Process of Cyclopentamine

There total 5 articles about Cyclopentamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-cyclopentyl-propan-2-one (1122-98-1) + methylamine (74-89-5) → cyclopentamine (102-45-4)

Guidance literature:

With aluminium; at 150 ℃; under 102971 Torr;

Reference yield:

2-cyclopentylacetonitrile (5732-87-6) → cyclopentamine (102-45-4)

Guidance literature:

Multi-step reaction with 2 steps

1: methyl magnesium iodide; diethyl ether

2: Raney nickel / 150 °C / 102971 Torr / Hydrogenation

With methyl magnesium iodide; diethyl ether; nickel;

Reference yield:

cyclopent-1-enyl-acetonitrile (22734-04-9) → cyclopentamine (102-45-4)

Guidance literature:

Multi-step reaction with 3 steps

1: palladium/charcoal; ethanol / Hydrogenation

2: methyl magnesium iodide; diethyl ether

3: Raney nickel / 150 °C / 102971 Torr / Hydrogenation

With palladium on activated charcoal; methyl magnesium iodide; diethyl ether; ethanol; nickel;

upstream raw materials:

1-cyclopentyl-propan-2-one

methylamine

(2-bromo-propyl)-cyclopentane

2-cyclopentyl-1-methyl-ethylamine