1-Phenyl-4-(5-phenyl-1,2-oxazol-3-yl)piperazine

Base Information

Chemical Name:1-Phenyl-4-(5-phenyl-1,2-oxazol-3-yl)piperazine
CAS No.:91076-79-8
Molecular Formula:C19H19N3O
Molecular Weight:305.379
Hs Code.:
DSSTox Substance ID:DTXSID30531059
Wikidata:Q82402623

Synonyms:91076-79-8;1-Phenyl-4-(5-phenyl-1,2-oxazol-3-yl)piperazine;UGSAVOIPRUAVPJ-UHFFFAOYSA-;DTXSID30531059;InChI=1/C19H19N3O/c1-3-7-16(8-4-1)18-15-19(20-23-18)22-13-11-21(12-14-22)17-9-5-2-6-10-17/h1-10,15H,11-14H2

Suppliers and Price of 1-Phenyl-4-(5-phenyl-1,2-oxazol-3-yl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 1-Phenyl-4-(5-phenyl-1,2-oxazol-3-yl)piperazine

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:305.152812238
Heavy Atom Count:23
Complexity:358

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1C2=CC=CC=C2)C3=NOC(=C3)C4=CC=CC=C4

Technology Process of 1-Phenyl-4-(5-phenyl-1,2-oxazol-3-yl)piperazine

There total 3 articles about 1-Phenyl-4-(5-phenyl-1,2-oxazol-3-yl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 91076-85-6
3-methylthio-3-N-(N'-phenyl)piperazino-1-phenyl-2-propen-1-one

: 91076-79-8
5-phenyl-3-(4-phenylpiperazinyl)isoxazole

Guidance literature:: With potassium hydroxide; hydroxylamine hydrochloride; In ethanol; for 4h; Heating;
DOI:10.1055/s-1984-30793

Reference yield:

: 86662-37-5
benzoylthioacetic acid N-phenylpiperazide

: 91076-79-8
5-phenyl-3-(4-phenylpiperazinyl)isoxazole

Guidance literature:: With hydroxylamine; In ethanol; pH=7; regioselective reaction; Reflux;
DOI:10.1002/ejoc.201300038

Reference yield:

: 92-54-6
4-phenyl-1-piperazine

: 20365-21-3
methyl 3-oxo-3-phenylpropanedithioate

: 91076-79-8
5-phenyl-3-(4-phenylpiperazinyl)isoxazole

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / Reflux

2: hydroxylamine / ethanol / pH 7 / Reflux

With hydroxylamine; In ethanol;
DOI:10.1002/ejoc.201300038