2-(4-METHYLPHENYL)ACETOPHENONE

Base Information

• Chemical Name: 2-(4-METHYLPHENYL)ACETOPHENONE
• CAS No.: 2430-99-1
• Molecular Formula: C15H14O
• Molecular Weight: 210.276
• Hs Code.: 2914399090
• Mol file: 2430-99-1.mol

Synonyms:Acetophenone,2-p-tolyl- (6CI,7CI,8CI);2-(4-Methylphenyl)-1-phenylethanone;2-p-Tolylacetophenone;4-Methylbenzyl phenyl ketone;NSC 51154;Phenylp-tolylmethyl ketone;

Chemical Property of 2-(4-METHYLPHENYL)ACETOPHENONE

Chemical Property:

• Vapor Pressure: 0.000102mmHg at 25°C
• Melting Point: 95 °C
• Refractive Index: 1.576
• Boiling Point: 337.9 °C at 760 mmHg
• Flash Point: 145 °C
• PSA: 17.07000
• Density: 1.062 g/cm³
• LogP: 3.42040
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

2-(4-Methylphenyl)acetophenone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(4-METHYLPHENYL)ACETOPHENONE

There total 94 articles about 2-(4-METHYLPHENYL)ACETOPHENONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

para-chlorotoluene (106-43-4) + acetophenone (98-86-2) → 1-phenyl-2-p-tolylethanone (2430-99-1)

Guidance literature:

With C₄₁H₄₆Cl₂FeN₄Pd; potassium tert-butylate; In 1,4-dioxane; at 100 ℃; for 3h; Inert atmosphere;

DOI:10.1071/CH12035

Reference yield: 92.0%

(4-methylphenyl)acetonitrile (2947-61-7) + phenylboronic acid (98-80-6) → 1-phenyl-2-p-tolylethanone (2430-99-1)

Guidance literature:

With [2,2]bipyridinyl; palladium diacetate; trifluoroacetic acid; In tetrahydrofuran; water; at 80 ℃; for 36h; Schlenk technique; Inert atmosphere;

DOI:10.1055/s-0033-1338909

Reference yield: 91.0%

para-bromotoluene (106-38-7) + acetophenone (98-86-2) → 1-phenyl-2-p-tolylethanone (2430-99-1)

Guidance literature:

With C₁₆H₁₄N₆O₄Pd; potassium tert-butylate; In acetonitrile; at 82 ℃; for 2h; Schlenk technique; Reflux;

DOI:10.1007/s11243-017-0148-6

upstream raw materials:

2-phenyl-3-p-tolyl-oxirane

(E)-3-Ureido-but-2-enoic acid ethyl ester

1-chloroacetophenone

toluene

Downstream raw materials:

benzoic acid

2-oxo-2-phenyl-1-(p-tolyl)ethyl acetate

ethyl 1,5-diphenyl-4-p-tolyl-1H-pyrazole-3-carboxylate

(E)-1-(4-methylphenyl)-2-phenyl-1-[(4-methylphenyl)sulfonyl]ethylene