2-(1-Methyl-5-oxopyrrolidin-2-yl)acetic acid

Base Information

Chemical Name:2-(1-Methyl-5-oxopyrrolidin-2-yl)acetic acid
CAS No.:60307-25-7
Molecular Formula:C7H11NO3
Molecular Weight:157.169
Hs Code.:
European Community (EC) Number:262-154-7
UNII:V1XTB9G7MF
DSSTox Substance ID:DTXSID70975716
Nikkaji Number:J25.992F,J25.993D,J11.813C
Wikidata:Q27291422

Synonyms:2-(1-methyl-5-oxopyrrolidin-2-yl)acetic acid;60307-25-7;Ergoninic acid;UNII-V1XTB9G7MF;V1XTB9G7MF;(1)-1-Methyl-5-oxopyrrolidine-2-acetic acid;EINECS 262-154-7;(1-methyl-5-oxopyrrolidin-2-yl)acetic acid;495-95-4;ecgoninic acid;Ecgonic acid;d-Ecgonic acid;l-Ecgonic acid;(+/-)-ECGONINIC ACID;SCHEMBL17938745;DTXSID70975716;AKOS006346059;AT19055;2-Pyrrolidineacetic acid, 1-methyl-5-oxo-;CS-0239213;2-(1-methyl-5-oxopyrrolidin-2-yl)aceticacid;(+-)-1-methyl-5-oxopyrrolidine-2-acetic acid;EN300-207765;Q27291422;F1913-0460;Z1201625519;2-PYRROLIDINEACETIC ACID, 1-METHYL-5-OXO-, (+/-)-

Suppliers and Price of 2-(1-Methyl-5-oxopyrrolidin-2-yl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-(1-Methyl-5-oxopyrrolidin-2-yl)acetic acid

Chemical Property:

Vapor Pressure:1.36E-06mmHg at 25°C
Boiling Point:373.1°Cat760mmHg
Flash Point:179.4°C
Density:1.223g/cm³
XLogP3:-0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:157.07389321
Heavy Atom Count:11
Complexity:190

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(CCC1=O)CC(=O)O

Technology Process of 2-(1-Methyl-5-oxopyrrolidin-2-yl)acetic acid

There total 9 articles about 2-(1-Methyl-5-oxopyrrolidin-2-yl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 18715-38-3
trans-1,4-dicyano-2-butene

: 60307-25-7,495-95-4
(1-methyl-5-oxo-pyrrolidin-2-yl)-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: aqueous hydrochloric acid

2: 210 °C

With hydrogenchloride;
DOI:10.1021/ja01162a104

Reference yield:

: 29311-53-3
(E)-3-hexene-1,6-dioic acid

: 74-89-5
methylamine

: 60307-25-7,495-95-4
(1-methyl-5-oxo-pyrrolidin-2-yl)-acetic acid

Guidance literature:: at 210 ℃;
DOI:10.1021/ja01162a104

Reference yield:

: 867-13-0
diethoxyphosphoryl-acetic acid ethyl ester

: 41194-00-7
5-Hydroxy-N-methyl-2-pyrrolidone

: 60307-25-7,495-95-4
(1-methyl-5-oxo-pyrrolidin-2-yl)-acetic acid

Guidance literature:: diethoxyphosphoryl-acetic acid ethyl ester; With sodium hydride; In toluene; mineral oil; at 80 ℃; for 0.5h; Inert atmosphere;

5-Hydroxy-N-methyl-2-pyrrolidone; In toluene; mineral oil; at 80 ℃; for 3h; Inert atmosphere;

With water; sodium hydroxide; In toluene; mineral oil; at 20 ℃; for 12h;
DOI:10.1002/adsc.201600603