4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N,N-dimethylbenzenesulfonamide

Base Information

Chemical Name:4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N,N-dimethylbenzenesulfonamide
CAS No.:92082-85-4
Molecular Formula:C16H14N2O4S
Molecular Weight:330.364
Hs Code.:

Synonyms:4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-N,N-dimethyl-benzenesulfonamide;p-Phthalimidobenzenesulfonyl-N,N-dimethylamide;

Suppliers and Price of 4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N,N-dimethylbenzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Aronis compounds
4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N,N-dimethylbenzenesulfonamide
10mg
$ 20.00

Aronis compounds
4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N,N-dimethylbenzenesulfonamide
1mg
$ 12.00

Total 1 raw suppliers

Chemical Property of 4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N,N-dimethylbenzenesulfonamide

Chemical Property:

Melting Point:242 - 244 °C
PSA：83.14000
LogP:2.88330

Purity/Quality:: 4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N,N-dimethylbenzenesulfonamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N,N-dimethylbenzenesulfonamide

There total 4 articles about 4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N,N-dimethylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 4435-59-0
4-(1,3-dioxo-2,3-dihydro-1H-2-isoindolyl)-1-benzenesulfonyl chloride

: 124-40-3
dimethyl amine

: 92082-85-4
4-(1,3-dioxoisoindolin-2-yl)-N,N-dimethyl benzenesulphonamide

Guidance literature:: With pyridine; In dichloromethane; at 0 - 20 ℃;
DOI:10.1016/j.bioorg.2015.07.005

Reference yield:

: 520-03-6
N-phenylphthalimide

: 92082-85-4
4-(1,3-dioxoisoindolin-2-yl)-N,N-dimethyl benzenesulphonamide

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / ClSO₃H / 2 h / 30 - 75 °C

2: 56 percent / methanol / 1 h / Ambient temperature

With chlorosulfonic acid; In methanol;

Reference yield:

: 62-53-3
aniline

: 92082-85-4
4-(1,3-dioxoisoindolin-2-yl)-N,N-dimethyl benzenesulphonamide

Guidance literature:: Multi-step reaction with 3 steps

1: acetic acid / 120 °C / Inert atmosphere

2: chlorosulfonic acid; phosphorus pentachloride / dichloromethane / 0.5 h / 0 - 60 °C

3: pyridine / dichloromethane / 0 - 20 °C

With pyridine; chlorosulfonic acid; phosphorus pentachloride; acetic acid; In dichloromethane;
DOI:10.1016/j.bioorg.2015.07.005