Ethyl 2-(4-fluorophenyl)-2-hydroxyacetate

Base Information

Chemical Name:Ethyl 2-(4-fluorophenyl)-2-hydroxyacetate
CAS No.:7550-03-0
Molecular Formula:C10H11 F O3
Molecular Weight:198.194
Hs Code.:2918199090
European Community (EC) Number:231-438-2
DSSTox Substance ID:DTXSID20996956
Nikkaji Number:J307.876K
Mol file:7550-03-0.mol

Synonyms:ethyl 2-(4-fluorophenyl)-2-hydroxyacetate;7550-03-0;Ethyl 4-fluorophenylglycolate;ethyl (4-fluorophenyl)(hydroxy)acetate;EINECS 231-438-2;SCHEMBL512526;AMY5884;DTXSID20996956;CS3001;MFCD16661866;AKOS009165450;AS-9745;SB46002;ethyl2-(4-fluorophenyl)-2-hydroxyacetate;EN300-624326;Hydroxy(4-fluorophenyl)acetic acid ethyl ester

Suppliers and Price of Ethyl 2-(4-fluorophenyl)-2-hydroxyacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
Ethyl (4-fluorophenyl)(hydroxy)acetate
1 g
$ 160.00

Matrix Scientific
Ethyl (4-fluorophenyl)(hydroxy)acetate
1g
$ 365.00

Atlantic Research Chemicals
Ethyl2-(4-Fluorophenyl)-2-hydroxyacetate 95%
250mgs:
$ 137.85

Abosyn
ethyl2-(4-fluorophenyl)-2-hydroxyacetate 95%-98%
1g
$ 350.00

Total 11 raw suppliers

Chemical Property of Ethyl 2-(4-fluorophenyl)-2-hydroxyacetate

Chemical Property:

Vapor Pressure:0.00139mmHg at 25°C
Boiling Point:284.5°C at 760 mmHg
Flash Point:125.9°C
PSA：46.53000
Density:1.229g/cm³
LogP:1.42220
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:198.06922237
Heavy Atom Count:14
Complexity:188

Purity/Quality:

99%, ^*data from raw suppliers

Ethyl (4-fluorophenyl)(hydroxy)acetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C1=CC=C(C=C1)F)O

Technology Process of Ethyl 2-(4-fluorophenyl)-2-hydroxyacetate

There total 8 articles about Ethyl 2-(4-fluorophenyl)-2-hydroxyacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 32222-45-0,52923-25-8,52950-15-9,395-33-5
4-fluoromandelic acid

: 75-03-6
ethyl iodide

: 7550-03-0
ethyl 2-(4-fluorophenyl)-2-hydroxyacetate

Guidance literature:: With caesium carbonate; In N,N-dimethyl-formamide; at 50 ℃;
DOI:10.1016/j.bmcl.2017.06.078

Reference yield: 99.0%

: 924-44-7
glyoxylic acid ethyl ester

: 1765-93-1
4-fluoroboronic acid

: 7550-03-0
ethyl 2-(4-fluorophenyl)-2-hydroxyacetate

Guidance literature:: With [Rh(OH)(cod)]2; (4aR,9aR)-6,8-dibenzyl-2,3-dimethoxy-2,3-dimethyl-3,4a,5,8,9,9a-hexahydro-2H-[1,4]dioxino[2,3-e][1,3]diazepin-6-ium hexafluorophosphate; potassium tert-butylate; In tert-Amyl alcohol; toluene; at 20 ℃; for 4h; Inert atmosphere;
DOI:10.1016/j.tet.2012.05.129