Propan-2-yl 2-(methylamino)acetate

Base Information

• Chemical Name: Propan-2-yl 2-(methylamino)acetate
• CAS No.: 93378-87-1
• Molecular Formula: C₆H₁₃NO₂
• Molecular Weight: 131.175
• European Community (EC) Number: 840-604-9
• Mol file: 93378-87-1.mol

Synonyms:propan-2-yl 2-(methylamino)acetate;93378-87-1;sarcosine isopropyl ester;(2-Propyl)-2-methylaminoacetate;Isopropyl methylglycinate;SCHEMBL807477;YRJZXBJXYOBRLR-UHFFFAOYSA-N;(2-propyl)-2-methyl aminoacetate;AKOS009048582;CS-0263335;EN300-862768;G27163

Chemical Property of Propan-2-yl 2-(methylamino)acetate

Chemical Property:

• XLogP3: 0.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 131.094628657
• Heavy Atom Count: 9
• Complexity: 91.1

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C)OC(=O)CNC

Technology Process of Propan-2-yl 2-(methylamino)acetate

There total 2 articles about Propan-2-yl 2-(methylamino)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

isopropyl 2-bromoacetate (29921-57-1) + methylamine (74-89-5) → (2-propyl)-2-methylaminoacetate (93378-87-1)

Guidance literature:

In tetrahydrofuran; acetonitrile; at 20 ℃; for 4h;

DOI:10.1016/j.tet.2006.10.074

Reference yield:

isopropyl chloroacetate (105-48-6) + methylamine hydrochloride (593-51-1) → (2-propyl)-2-methylaminoacetate (93378-87-1)

Guidance literature:

methylamine hydrochloride; With triethylamine; In acetonitrile; at 15 ℃; for 1.5h;

isopropyl chloroacetate; In acetonitrile; at 20 ℃; for 10h;

DOI:10.1039/c4nj02308k

upstream raw materials:

isopropyl 2-bromoacetate

methylamine

isopropyl chloroacetate

methylamine hydrochloride