2,5-DIMETHYLHEXANEDIOIC ACID

Base Information

• Chemical Name: 2,5-DIMETHYLHEXANEDIOIC ACID
• CAS No.: 4454-18-6
• Molecular Formula: C8H14 O4
• Molecular Weight: 174.197
• Hs Code.: 2917190090
• Mol file: 4454-18-6.mol

Synonyms:2,5-Dimethyladipicacid; NSC 5947; NSC 89725; a,a'-Dimethyladipic acid

Chemical Property of 2,5-DIMETHYLHEXANEDIOIC ACID

Chemical Property:

• Vapor Pressure: 2.19E-05mmHg at 25°C
• Boiling Point: 335.9°Cat760mmHg
• Flash Point: 171.1°C
• PSA: 74.60000
• Density: 1.156g/cm³
• LogP: 1.20800
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

2,5-Dimethylhexanedioicacid 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,5-DIMETHYLHEXANEDIOIC ACID

There total 40 articles about 2,5-DIMETHYLHEXANEDIOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

n-pentyl methyl ketone (110-43-0) + carbon monoxide (201230-82-2) → 2,5-dimethyladipic acid (4454-18-6) + α-methyl-δ-oxocaproic acid (54248-02-1) + 6-oxo-2-methyl-heptanoic acid (2570-68-5)

Guidance literature:

With hydrogen fluoride; antimony pentafluoride; at 20 ℃; for 3h; Product distribution; Mechanism; formation of oxo carboxylic acids; further alkyl methyl ketones;

DOI:10.1246/cl.1983.19

Reference yield:

dimethyl 2,5-dimethylhexanedioate (19550-58-4) → 2,5-dimethyladipic acid (4454-18-6)

Guidance literature:

With water; lithium hydroxide; In tetrahydrofuran; at 20 ℃; for 48h;

Reference yield:

(+)-thiolactic acid (6959-64-4) + poly(methacrylic acid) (79-41-4,25087-26-7,50867-57-7) → 2,5-dimethyladipic acid (4454-18-6)

Guidance literature:

With hydrogenchloride; sodium hydroxide; In water;

upstream raw materials:

2,5-dimethyltetrahydrofuran

2,5-dimethyl-adipic acid diethyl ester

hex-1-ene-2,5-dicarboxylic acid

2,5-dimethyl-1,6-hexanedial

Downstream raw materials:

2,5-dimethylcyclopentanone

2,5-Dimethyl-hexane-bis-thioic acid di-S-p-tolyl ester

(E),(E)-2,5-Di(methoxycarbonyl)-hexa-2,4-dien

dimethyl 2,5-dimethylhexanedioate

Refernces

• 1、 -. "CONJUGATES OF CARTILAGE-HOMING PEPTIDES". Paragraph 0359; 0361. . Retrieved 2019/11/12.
• 2、 -. "Process for the preparation of N-thienyl-chloroacetamides". . . Retrieved 2008/06/13.