Methyl 4-chloro-3-hydrazinylbenzoate

Base Information

Chemical Name:Methyl 4-chloro-3-hydrazinylbenzoate
CAS No.:89981-25-9
Molecular Formula:C8H9ClN2O2
Molecular Weight:200.625
Hs Code.:
NSC Number:158078
DSSTox Substance ID:DTXSID501009078
Wikidata:Q83005770

Synonyms:methyl 4-chloro-3-hydrazinylbenzoate;89981-25-9;NSC158078;SCHEMBL9144243;DSGSWTTVLFYPEL-UHFFFAOYSA-N;DTXSID501009078;Methyl 4-Chloro-3-hydrazinobenzoate;NSC-158078;FT-0721241

Suppliers and Price of Methyl 4-chloro-3-hydrazinylbenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Methyl 4-chloro-3-hydrazinylbenzoate

Chemical Property:

Vapor Pressure:0.00039mmHg at 25°C
Boiling Point:317.2°Cat760mmHg
Flash Point:145.7°C
Density:1.375g/cm³
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:200.0352552
Heavy Atom Count:13
Complexity:189

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC(=C(C=C1)Cl)NN

Technology Process of Methyl 4-chloro-3-hydrazinylbenzoate

There total 4 articles about Methyl 4-chloro-3-hydrazinylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.9%

: 40872-87-5
methyl 3-amino-4-chlorobenzoate

: 89981-25-9
5-(carbomethoxy)-2-chlorophenylhydrazine

Guidance literature:: methyl 3-amino-4-chlorobenzoate; With hydrogenchloride; sodium nitrite; In water; at 0 ℃; for 0.5h;

With tin(ll) chloride; at 0 ℃; for 4h;
DOI:10.1016/j.bmc.2019.01.009

Reference yield:

: tin(II)chloride dihydrate

: 75-09-2
dichloromethane

: 40872-87-5
methyl 3-amino-4-chlorobenzoate

: 89981-25-9
5-(carbomethoxy)-2-chlorophenylhydrazine

Guidance literature:: With sodium nitrite; In hydrogenchloride; water; ethyl acetate;

Reference yield:

: 2840-28-0
3-amino-4-chloro-benzoic acid

: 89981-25-9
5-(carbomethoxy)-2-chlorophenylhydrazine

Guidance literature:: Multi-step reaction with 2 steps

1.1: thionyl chloride / 3 h / Reflux

2.1: hydrogenchloride; sodium nitrite / water / 0.5 h / 0 °C

2.2: 4 h / 0 °C

With hydrogenchloride; thionyl chloride; sodium nitrite; In water;
DOI:10.1016/j.bmc.2019.01.009