Ropivacaine-ET-S

Base Information

Chemical Name:Ropivacaine-ET-S
CAS No.:98626-59-6
Molecular Formula:C₁₆H₂₄N₂O
Molecular Weight:260.379
Hs Code.:

Synonyms:2-Piperidinecarboxamide,N-(2,6-dimethylphenyl)-1-ethyl-,(2S);N-(2,6-Dimethylphenyl)-1-ethylpiperidine-2-carboxamide,(S);(-)-(2S)-N-(2,6-Dimethylphenyl)-1-ethylpiperidine-2-carboxamide;Ropivacaine hydrochloride monohydrate impurity D [EP];2-Piperidinecarboxamide,N-(2,6-dimethylphenyl)-1-ethyl-,(S);UNII-93FC6DB9MS;

Suppliers and Price of Ropivacaine-ET-S

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-2-DesmethylRopivacaine
1g
$ 1455.00

Total 9 raw suppliers

Chemical Property of Ropivacaine-ET-S

Chemical Property:

Melting Point:142 - 144°C
Boiling Point:396.8±42.0 °C(Predicted)
PKA:14.85±0.70(Predicted)
PSA：35.83000
Density:1.057±0.06 g/cm3(Predicted)
LogP:3.70370
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99%, ^*data from raw suppliers

N-2-DesmethylRopivacaine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses N-2-Desmethyl Ropivacaine (Ropivacaine EP Impurity D) is an impurity of (S)-Ropivacaine (R674995), that acts as a local anaesthetic for use during medical procedures. Frequently used in epidural procedures as a labor analgesia.

Technology Process of Ropivacaine-ET-S

There total 7 articles about Ropivacaine-ET-S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 64-17-5
ethanol

: 27262-40-4
(S)-2',6'-pipecoloxylidide

: 2180-94-1,98626-59-6
1-ethyl-piperidine-2-carboxylic acid-(2,6-dimethyl-anilide)

: (R)-2',6'-pipecoloxylidide

Guidance literature:: With 1-hydroxytetraphenylcyclopentadienyl(tetraphenyl-2,4-cyclopentadien-1-one)-μ-hydrotetracarbonyldiruthenium(II); In dibutyl ether; at 120 ℃; for 7h; Inert atmosphere;
DOI:10.1016/j.tetlet.2010.07.051