1,2-Phenylenedimethanamine

Base Information

• Chemical Name: 1,2-Phenylenedimethanamine
• CAS No.: 17300-02-6
• Molecular Formula: C8H12N2
• Molecular Weight: 136.197
• Hs Code.: 2921590090
• European Community (EC) Number: 605-656-7
• DSSTox Substance ID: DTXSID60330719
• Nikkaji Number: J153.455F
• Wikidata: Q82095270
• Mol file: 17300-02-6.mol

Synonyms:1,2-Phenylenedimethanamine;17300-02-6;2-Aminomethyl-benzylamine;Benzenedimethanamine;[2-(aminomethyl)phenyl]methanamine;o-Xylylenediamine;xylylenediamine;AKOS AUF2082;2-aminomethylbenzylamine;o-Xylylenediamine, 95%;SCHEMBL15247;DTXSID60330719;alpha,alpha'-Diamino-ortho-xylene;MFCD06212556;AKOS004114629;[2-(aminomethyl)-phenyl]-methyl-amine;SB34246;AS-30172;CS-0156045;FT-0721068;1-[2-(AMINOMETHYL)PHENYL]METHANAMINE;EN300-316554;A881817;alpha,alpha'-Diamino-o-xylene, 1,2-Bis(aminomethyl)benzene, ortho-Phenylene-bis(methylamine)

Chemical Property of 1,2-Phenylenedimethanamine

Chemical Property:

• Boiling Point: 253.8 °C at 760 mmHg
• Flash Point: 125.8 °C
• PSA: 52.04000
• Density: 1.052 g/cm³
• LogP: 2.00460
• Storage Temp.: 2-8°C
• XLogP3: -0.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 136.100048391
• Heavy Atom Count: 10
• Complexity: 81.3

Purity/Quality:

97% ^*data from raw suppliers

o-Xylylenediamine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 22-34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)CN)CN

Technology Process of 1,2-Phenylenedimethanamine

There total 23 articles about 1,2-Phenylenedimethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

phthalonitrile (91-15-6) → 1,2-benzenedimethanamine (17300-02-6)

Guidance literature:

With sodium tetrahydroborate; copper ferrite; In water; for 0.216667h; chemoselective reaction; Reflux; Green chemistry;

DOI:10.1007/s11164-019-03794-4

Reference yield: 86.0%

1,2-bis(azidomethyl)benzene (102437-79-6) → 1,2-benzenedimethanamine (17300-02-6)

Guidance literature:

With water; triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 2h;

DOI:10.1021/ol203364b

Reference yield: 73.0%

1,4-Dihydrophthalazine (50399-98-9) → 1,2-benzenedimethanamine (17300-02-6)

Guidance literature:

With pyridine; palladium on activated charcoal; hydrogen; In methanol; at 20 ℃; for 0.25h; under 760.051 Torr; Green chemistry;

DOI:10.1039/d1ob00850a

upstream raw materials:

PHTHALAZINE

urea

α,α'-dibromo-o-xylene

o-xylylenebisurea

Downstream raw materials:

isoindoline

1,2-Bis<<(p-tolylsulfonyl)amino>methyl>benzene

2-phenyl-5,6-benzo-1,3,2-diazaphosphepane

2-phenoxy-5,6-benzo-1,3,2-diazaphosphepane