4-Chloro-7-methoxy-1-indanone

Base Information

Chemical Name:4-Chloro-7-methoxy-1-indanone
CAS No.:99183-99-0
Molecular Formula:C₁₀H₉ClO₂
Molecular Weight:196.633
Hs Code.:
DSSTox Substance ID:DTXSID80562555
Wikidata:Q82446773
Mol file:99183-99-0.mol

Synonyms:4-Chloro-7-methoxy-1-indanone;99183-99-0;4-chloro-7-methoxy-2,3-dihydro-1H-inden-1-one;1H-Inden-1-one, 4-chloro-2,3-dihydro-7-methoxy-;4-chloro-7-methoxy-2,3-dihydroinden-1-one;SCHEMBL9500995;DTXSID80562555;AM1237;AKOS006312108;AC-23391

Suppliers and Price of 4-Chloro-7-methoxy-1-indanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-CHLORO-7-METHOXY-1-INDANONE 95.00%
5MG
$ 501.66

Total 18 raw suppliers

Chemical Property of 4-Chloro-7-methoxy-1-indanone

Chemical Property:

Boiling Point:347.7±42.0 °C(Predicted)
PSA：26.30000
Density:1.302±0.06 g/cm3(Predicted)
LogP:2.47750
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:196.0291072
Heavy Atom Count:13
Complexity:217

Purity/Quality:

99%, ^*data from raw suppliers

4-CHLORO-7-METHOXY-1-INDANONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C2C(=C(C=C1)Cl)CCC2=O

Technology Process of 4-Chloro-7-methoxy-1-indanone

There total 3 articles about 4-Chloro-7-methoxy-1-indanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 3438-16-2
5-chloro-2-methoxybenzoic acid

: 108-59-8
malonic acid dimethyl ester

: 99183-99-0
4-chloro-7-methoxy-2,3-dihydro-1H-inden-1-one

Guidance literature:: With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; sodium acetate; at 160 ℃; for 12h; regioselective reaction; Inert atmosphere; Schlenk technique;
DOI:10.1021/acs.orglett.0c02986

Reference yield:

: 127033-12-9
4-fluorophenyl 3-chloropropanoate

: 74-88-4
methyl iodide

: 99183-99-0
4-chloro-7-methoxy-2,3-dihydro-1H-inden-1-one

: 127033-13-0
4-fluoro-7-methoxy-1-indanone

Guidance literature:: With aluminium trichloride; potassium carbonate; Multistep reaction; 1.) 25 deg C to 180 deg C, 2.) acetone;
DOI:10.1021/jm00168a002