7-Bromo-2-chloro-4-(4-morpholinyl)-thieno[3,2-d]pyrimidine

Base Information

Chemical Name:7-Bromo-2-chloro-4-(4-morpholinyl)-thieno[3,2-d]pyrimidine
CAS No.:1033743-85-9
Molecular Formula:C10H9BrClN3OS
Molecular Weight:334.62
Hs Code.:
DSSTox Substance ID:DTXSID20701461
Wikidata:Q72453108
Mol file:1033743-85-9.mol

Synonyms:1033743-85-9;7-Bromo-2-chloro-4-(4-morpholinyl)-thieno[3,2-d]pyrimidine;4-(7-bromo-2-chlorothieno[3,2-d]pyrimidin-4-yl)morpholine;SCHEMBL1284337;DTXSID20701461;HQVYWSMLUMSBBG-UHFFFAOYSA-N;FT-0737583;7-Bromo-2-chloro-4-(morpholin-4-yl)thieno[3,2-d]pyrimidine;7-bromo-2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidine

Suppliers and Price of 7-Bromo-2-chloro-4-(4-morpholinyl)-thieno[3,2-d]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
4-(7-Bromo-2-chlorothieno[3,2-d]pyrimidin-4-yl)morpholine
50mg
$ 1000.00

Total 3 raw suppliers

Chemical Property of 7-Bromo-2-chloro-4-(4-morpholinyl)-thieno[3,2-d]pyrimidine

Chemical Property:

PSA：66.49000
Density:1.752
LogP:3.00880
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:332.93382
Heavy Atom Count:17
Complexity:282

Purity/Quality:

99% ^*data from raw suppliers

4-(7-Bromo-2-chlorothieno[3,2-d]pyrimidin-4-yl)morpholine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1C2=NC(=NC3=C2SC=C3Br)Cl

Technology Process of 7-Bromo-2-chloro-4-(4-morpholinyl)-thieno[3,2-d]pyrimidine

There total 5 articles about 7-Bromo-2-chloro-4-(4-morpholinyl)-thieno[3,2-d]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.7%

: 110-91-8,99108-56-2
morpholine

: 41102-25-4
7-bromo-2,4-dichloroimidazo[2,1-f][1,2,4]triazine

: 1033743-85-9
4-(7-bromo-2-chlorothieno[3,2-d]pyrimidin-4-yl)morpholine

Guidance literature:: In methanol; at 20 ℃; for 2h;

Reference yield:

: 16233-51-5
1H-thieno[3,2-d]pyrimidine-2,4-dione

: 1033743-85-9
4-(7-bromo-2-chlorothieno[3,2-d]pyrimidin-4-yl)morpholine

Guidance literature:: Multi-step reaction with 3 steps

1: bromine; acetic acid / 70 °C

2: trichlorophosphate / 12 h / Reflux

3: methanol / 2 h / 20 °C

With bromine; acetic acid; trichlorophosphate; In methanol;

Reference yield:

: 41102-02-7
7-bromothieno[3,2-d]pyrimidine-2,4(1H,3H)-dione

: 1033743-85-9
4-(7-bromo-2-chlorothieno[3,2-d]pyrimidin-4-yl)morpholine

Guidance literature:: Multi-step reaction with 2 steps

1: trichlorophosphate / 12 h / Reflux

2: methanol / 2 h / 20 °C

With trichlorophosphate; In methanol;