3-Amino-5-methoxyisonicotinic acid

Base Information

Chemical Name:3-Amino-5-methoxyisonicotinic acid
CAS No.:82673-73-2
Molecular Formula:C₇H₈N₂O₃
Molecular Weight:168.152
Hs Code.:2933399090
European Community (EC) Number:675-800-1
DSSTox Substance ID:DTXSID50513615
Nikkaji Number:J2.045.428H
Wikidata:Q82373520
Mol file:82673-73-2.mol

Synonyms:3-Amino-5-methoxyisonicotinic acid;82673-73-2;3-amino-5-methoxypyridine-4-carboxylic acid;3-AMINO-5-METHOXYISONICOTINICACID;3-Amino-5-methoxy-isonicotinic acid;SCHEMBL15645276;DTXSID50513615;FEPJDBLYVHAGMW-UHFFFAOYSA-N;AMY15164;MFCD11052852;AKOS006309205;AB63055;AS-36020;CS-0172653;FT-0765077;3-Amino-5-methoxyisonicotinic acid, AldrichCPR;A917427

Suppliers and Price of 3-Amino-5-methoxyisonicotinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Amino-5-methoxyisonicotinicacid
100mg
$ 250.00

Matrix Scientific
3-Amino-5-methoxyisonicotinic acid
750mg
$ 289.00

Crysdot
3-Amino-5-methoxyisonicotinicacid 97%
5g
$ 680.00

AstaTech
3-AMINO-5-METHOXYISONICOTINICACID 97%
1 / G
$ 385.00

AstaTech
3-AMINO-5-METHOXYISONICOTINICACID 97%
0.25 / G
$ 154.00

AstaTech
3-AMINO-5-METHOXYISONICOTINICACID 97%
5 / G
$ 1155.00

American Custom Chemicals Corporation
3-AMINO-5-METHOXY-ISONICOTINIC ACID 95.00%
250MG
$ 1012.94

Alichem
3-Amino-5-methoxyisonicotinicacid
5g
$ 1178.10

Alichem
3-Amino-5-methoxyisonicotinicacid
250mg
$ 166.32

Alichem
3-Amino-5-methoxyisonicotinicacid
1g
$ 396.55

Total 21 raw suppliers

Chemical Property of 3-Amino-5-methoxyisonicotinic acid

Chemical Property:

Vapor Pressure:1.21E-10mmHg at 25°C
Boiling Point:495.7°C at 760 mmHg
Flash Point:253.6°C
PSA：85.44000
Density:1.384g/cm³
LogP:0.95180
Storage Temp.:2-8°C
XLogP3:0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:168.05349212
Heavy Atom Count:12
Complexity:174

Purity/Quality:

97% ^*data from raw suppliers

3-Amino-5-methoxyisonicotinicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C(=CN=C1)N)C(=O)O

Technology Process of 3-Amino-5-methoxyisonicotinic acid

There total 1 articles about 3-Amino-5-methoxyisonicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 77903-35-6
3-Methoxy-5-(pivaloylamino)pyridine-4-carboxylic Acid

: 82673-73-2
3-amino-5-methoxypyridine-4-carboxylic acid

Guidance literature:: With hydrogenchloride; at 90 ℃; for 5h;

Reference yield: 55.0%

: 67-56-1
methanol

: 82673-73-2
3-amino-5-methoxypyridine-4-carboxylic acid

: 82673-74-3
methyl 3-amino-5-methoxypyridine-4-carboxylate

Guidance literature:: With hydrogenchloride; In methanol; for 2h; Ambient temperature;

Reference yield:

: 82673-73-2
3-amino-5-methoxypyridine-4-carboxylic acid

: 1589084-78-5
4-[5-methoxy-2-(2-phenylaminopyridin-4-yl)pyrido[3,4-d]pyrimidin-4-yl] piperazine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium methylate / methanol / 1 h / 20 °C / Inert atmosphere

1.2: 20 - 85 °C

2.1: triethylamine; dmap / N,N-dimethyl acetamide / 0.33 h / 20 °C / Sonication

2.2: 2.08 h / 20 °C / Sonication

2.3: 20 °C

3.1: sodium t-butanolate; bis(dibenzylideneacetone)-palladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene / 1,4-dioxane / 0.33 h / 150 °C / Microwave irradiation

With dmap; sodium methylate; triethylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; bis(dibenzylideneacetone)-palladium⁽⁰⁾; sodium t-butanolate; In 1,4-dioxane; methanol; N,N-dimethyl acetamide;