[4-(4-Aminophenoxy)(2-pyridyl)]-N-(methyl-d3)carboxamide

Base Information

Chemical Name:[4-(4-Aminophenoxy)(2-pyridyl)]-N-(methyl-d3)carboxamide
CAS No.:1189975-18-5
Molecular Formula:C13H10D3N3O2.
Molecular Weight:246.241
Hs Code.:
Mol file:1189975-18-5.mol

Synonyms:4-(4-Aminophenoxy)-N-(methyl-d3)-2-pyridinecarboxamide; 4-(4-Aminophenoxy)-N-(methyl-d3)picolinamide;4-[[2-[N-(Methyl-d3)carbamoyl]-4-pyridyl]oxy]aniline;;

Suppliers and Price of [4-(4-Aminophenoxy)(2-pyridyl)]-N-(methyl-d3)carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
[4-(4-Aminophenoxy)(2-pyridyl)]-N-(methyl-d3)carboxamide
1mg
$ 130.00

Medical Isotopes, Inc.
[4-(4-Aminophenoxy)(2-pyridyl)]-N-(methyl-d3)carboxamide
1 mg
$ 875.00

Total 6 raw suppliers

Chemical Property of [4-(4-Aminophenoxy)(2-pyridyl)]-N-(methyl-d3)carboxamide

Chemical Property:

PSA：77.24000
LogP:2.78780
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

[4-(4-Aminophenoxy)(2-pyridyl)]-N-(methyl-d3)carboxamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of [4-(4-Aminophenoxy)(2-pyridyl)]-N-(methyl-d3)carboxamide

There total 6 articles about [4-(4-Aminophenoxy)(2-pyridyl)]-N-(methyl-d3)carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1189858-48-7
4-chloropyridinyl-2-(N-1',1',1'-trideuteromethylcarboxamide)

: 123-30-8
4-amino-phenol

: 1189975-18-5
4-(4-aminophenoxy)-2-pyridine-(N-(methyl-d₃))carboxamide

Guidance literature:: 4-amino-phenol; With potassium tert-butylate; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

4-chloropyridinyl-2-(N-1',1',1'-trideuteromethylcarboxamide); With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃;

Reference yield:

: 53750-66-6
4-chloro-pyridine-2-carbonyl chloride

: 1189975-18-5
4-(4-aminophenoxy)-2-pyridine-(N-(methyl-d₃))carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: tetrahydrofuran / 5 h / 5 °C

2.1: potassium tert-butylate / N,N-dimethyl-formamide / 2 h / 20 °C

2.2: 80 °C

With potassium tert-butylate; In tetrahydrofuran; N,N-dimethyl-formamide;

Reference yield:

: 98-98-6
2-Picolinic acid

: 1189975-18-5
4-(4-aminophenoxy)-2-pyridine-(N-(methyl-d₃))carboxamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: thionyl chloride; N,N-dimethyl-formamide / 16.33 h / 40 - 72 °C / Reflux

2.1: tetrahydrofuran / 5 h / 5 °C

3.1: potassium tert-butylate / N,N-dimethyl-formamide / 2 h / 20 °C

3.2: 80 °C

With thionyl chloride; potassium tert-butylate; N,N-dimethyl-formamide; In tetrahydrofuran; N,N-dimethyl-formamide;