Ethyl 5-Methyloxazole-4-carboxylate

Base Information

Chemical Name:Ethyl 5-Methyloxazole-4-carboxylate
CAS No.:32968-44-8
Molecular Formula:C7H9NO3
Molecular Weight:155.153
Hs Code.:2934999090
European Community (EC) Number:963-354-3
DSSTox Substance ID:DTXSID70480754
Nikkaji Number:J3.428.728G
Wikidata:Q82315810
Mol file:32968-44-8.mol

Synonyms:Ethyl 5-Methyloxazole-4-carboxylate;32968-44-8;ethyl 5-methyl-1,3-oxazole-4-carboxylate;MFCD00105462;ETHYL5-METHYLOXAZOLE-4-CARBOXYLATE;Ethyl 5-Methyl-4-oxazolecarboxylate;5-METHYL-OXAZOLE-4-CARBOXYLIC ACID ETHYL ESTER;4-Oxazolecarboxylic acid, 5-methyl-, ethyl ester;5-methyl-4-oxazolecarboxylic acid ethyl ester;SCHEMBL13545974;DTXSID70480754;AMY18947;AKOS005138142;AB03428;SY020015;TS-02067;CS-0020160;EN300-128573;A821534;J-521149

Suppliers and Price of Ethyl 5-Methyloxazole-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl5-Methyl-4-oxazolecarboxylate
5 g
$ 655.00

J&W Pharmlab
5-Methyl-oxazole-4-carboxylicacidethylester 96%
100g
$ 2998.00

Crysdot
Ethyl5-methyloxazole-4-carboxylate 95+%
10g
$ 525.00

Crysdot
Ethyl5-methyloxazole-4-carboxylate 95+%
5g
$ 317.00

ChemScene
Ethyl5-methyl-1,3-oxazole-4-carboxylate
25g
$ 1133.00

ChemScene
Ethyl5-methyl-1,3-oxazole-4-carboxylate
1g
$ 132.00

ChemScene
Ethyl5-methyl-1,3-oxazole-4-carboxylate
250mg
$ 66.00

ChemScene
Ethyl5-methyl-1,3-oxazole-4-carboxylate
5g
$ 418.00

Chemenu
Ethyl5-methyloxazole-4-carboxylate 95%
10g
$ 496.00

Chemenu
Ethyl5-methyloxazole-4-carboxylate 95%
1g
$ 102.00

Total 23 raw suppliers

Chemical Property of Ethyl 5-Methyloxazole-4-carboxylate

Chemical Property:

Boiling Point:208.5±20.0 °C(Predicted)
PKA:-0.92±0.10(Predicted)
PSA：52.33000
Density:1.139±0.06 g/cm3(Predicted)
LogP:1.15970
Storage Temp.:2-8°C
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:155.058243149
Heavy Atom Count:11
Complexity:149

Purity/Quality:

99%, ^*data from raw suppliers

Ethyl5-Methyl-4-oxazolecarboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(OC=N1)C
Uses Ethyl 5-Methyl-4-oxazolecarboxylate is used in the synthesis of conglobatin which is a novel macrolide dilactone from Streptomyces conglobatus ATCC 31005.

Technology Process of Ethyl 5-Methyloxazole-4-carboxylate

There total 6 articles about Ethyl 5-Methyloxazole-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 2999-46-4
Ethyl isocyanoacetate

: 64-19-7,77671-22-8
acetic acid

: 32968-44-8
5-Methyl-4-oxazolcarbonsaeure-ethylester

Guidance literature:: acetic acid; With 1,1'-carbonyldiimidazole; In tetrahydrofuran; at 55 ℃; for 1h;

Ethyl isocyanoacetate; With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at 0 - 20 ℃; for 12h;
DOI:10.1007/s10593-019-02475-9

Reference yield: 65.0%

: 2999-46-4
Ethyl isocyanoacetate

: 75-36-5
acetyl chloride

: 32968-44-8
5-Methyl-4-oxazolcarbonsaeure-ethylester

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1002/chem.201101615

Reference yield: 26.0%

: 2999-46-4
Ethyl isocyanoacetate

: 127-17-3
2-oxo-propionic acid

: 32968-44-8
5-Methyl-4-oxazolcarbonsaeure-ethylester

Guidance literature:: 2-oxo-propionic acid; With potassium hydroxide; In isopropyl alcohol; Schlenk technique;

Ethyl isocyanoacetate; With dipotassium peroxodisulfate; 1,10-Phenanthroline; silver carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 12h; Schlenk technique; Inert atmosphere;
DOI:10.1039/c5cc02253c