Methyl 4-chloro-7-methoxyquinoline-6-carboxylate

Base Information

Chemical Name:Methyl 4-chloro-7-methoxyquinoline-6-carboxylate
CAS No.:205448-66-4
Molecular Formula:C12H10ClNO3
Molecular Weight:251.669
Hs Code.:2933499090
Mol file:205448-66-4.mol

Synonyms:6-Quinolinecarboxylic acid,4-chloro-7-methoxy-,methyl ester;methyl 4-chloro-7-methoxyquinoline-6-carboxylate;

Suppliers and Price of Methyl 4-chloro-7-methoxyquinoline-6-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Methyl-4-Chloro-7-methoxyquinoline-6-carboxylate
250mg
$ 333.00

SynQuest Laboratories
Methyl 4-chloro-7-methoxyquinoline-6-carboxylate
1 g
$ 540.00

Matrix Scientific
6-Quinolinecarboxylic acid 4-chloro-7-methoxy-methyl ester>95%
500mg
$ 750.00

Matrix Scientific
6-Quinolinecarboxylic acid 4-chloro-7-methoxy-methyl ester>95%
250mg
$ 492.00

Crysdot
Methyl4-chloro-7-methoxyquinoline-6-carboxylate 95+%
10g
$ 134.00

ChemScene
Methyl4-chloro-7-methoxyquinoline-6-carboxylate 99.96%
25g
$ 190.00

ChemScene
Methyl4-chloro-7-methoxyquinoline-6-carboxylate 99.96%
10g
$ 110.00

ChemScene
Methyl4-chloro-7-methoxyquinoline-6-carboxylate 99.96%
5g
$ 60.00

Chemenu
methyl4-chloro-7-methoxyquinoline-6-carboxylate 95%
25g
$ 524.00

Chemenu
methyl4-chloro-7-methoxyquinoline-6-carboxylate 95%
5g
$ 168.00

Total 99 raw suppliers

Chemical Property of Methyl 4-chloro-7-methoxyquinoline-6-carboxylate

Chemical Property:

Boiling Point:377.4±37.0 °C(Predicted)
PKA:2.98±0.30(Predicted)
PSA：48.42000
Density:1.320±0.06 g/cm3(Predicted)
LogP:2.68340
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

Methyl-4-Chloro-7-methoxyquinoline-6-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Methyl-4-Chloro-7-methoxyquinoline-6-carboxylate is used pharmaceutically for treating infection after burns. It is also used as reagents in the preparation of naphthamides as inhibitors of vascular endothelial growth factor (VEGF) receptor tyrosine kinase.

Technology Process of Methyl 4-chloro-7-methoxyquinoline-6-carboxylate

There total 8 articles about Methyl 4-chloro-7-methoxyquinoline-6-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.53%

: 205448-65-3
7-methoxy-4-oxo-1,4-dihydroquinoline-6-carboxylic acid methyl ester

: 205448-66-4
methyl 4-chloro-7-methoxyquinoline-6-carboxylate

Guidance literature:: With trichlorophosphate; In toluene; at 25 - 95 ℃;

Reference yield: 92.8%

: methyl 4-hydroxy-7-methoxyquinoline-6-carboxylate

: 205448-66-4
methyl 4-chloro-7-methoxyquinoline-6-carboxylate

Guidance literature:: With thionyl chloride; at 100 ℃; for 5h; Temperature;

Reference yield:

: 205448-65-3
7-methoxy-4-oxo-1,4-dihydroquinoline-6-carboxylic acid methyl ester

: 75-09-2
dichloromethane

: 205448-66-4
methyl 4-chloro-7-methoxyquinoline-6-carboxylate

Guidance literature:: 7-methoxy-4-oxo-1,4-dihydroquinoline-6-carboxylic acid methyl ester; In dimethyl sulfoxide; N,N-dimethyl-formamide; at 125 ℃; for 3h;

dichloromethane; With sodium hydrogencarbonate; at 20 - 25 ℃; Solvent; Temperature;